@article{80f9a09bc2b440d39268d530f2e1008e,
title = "Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility",
abstract = "Purpose: To identify demographic, (bio)physical, behavioral, and psychological determinants of successful lifestyle change and program completion by performing a secondary analysis of the intervention arm of a randomized-controlled trial, investigating a preconception lifestyle intervention. Methods: The 6-month lifestyle intervention consisted of dietary counseling, physical activity, and behavioral modification, and was aimed at 5–10% weight loss. We operationalized successful lifestyle change as successful weight loss (≥ 5% weight/BMI ≤ 29 kg/m2), weight loss in kilograms, a reduction in energy intake, and an increase in physical activity during the intervention program. We performed logistic and mixed-effect regression analyses to identify baseline factors that were associated with successful change or program completion. Results: Women with higher external eating behavior scores had higher odds of successful weight loss (OR 1.10, 95% CI 1.05–1.16). Women with the previous dietetic support lost 0.94 kg less during the intervention period (95% CI 0.01–1.87 kg). Women with higher self-efficacy reduced energy intake more than women with lower self-efficacy (p < 0.01). Women with an older partner had an increased energy intake (6 kcal/year older, 95% CI 3–13). A high stage of change towards physical activity was associated with a higher number of daily steps (p = 0.03). A high stage of change towards weight loss was associated with completion of the intervention (p = 0.04). Conclusions: Determinants of lifestyle change and program completion were: higher external eating behavior, not having received previous dietetic support, high stage of change. This knowledge can be used to identify women likely to benefit from lifestyle interventions and develop new interventions for women requiring alternative support. Trial registration: The LIFEstyle study was registered at the Dutch trial registry (NTR 1530; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1530).",
keywords = "Determinants, Lifestyle intervention, Obesity, Preconception",
author = "{the LIFEstyle study group} and Karsten, {Matty D.A.} and {van Oers}, {Anne M.} and Henk Groen and Mutsaerts, {Meike A.Q.} and {van Poppel}, {Mireille N.M.} and Anouk Geelen and {van de Beek}, Cornelieke and Painter, {Rebecca C.} and Mol, {Ben W.J.} and Roseboom, {Tessa J.} and Annemieke Hoek and Burggraaff, {J. M.} and Kuchenbecker, {W. K.H.} and Perquin, {D. A.M.} and Koks, {C. A.M.} and {van Golde}, R. and Kaaijk, {E. M.} and Schierbeek, {J. M.} and Oosterhuis, {G. J.E.} and Broekmans, {F. J.} and Vogel, {N. E.A.} and Lambalk, {C. B.} and {van der Veen}, F. and Klijn, {N. F.} and Mercelina, {P. E.A.M.} and {van Kasteren}, {Y. M.} and Nap, {A. W.} and Mulder, {R. J.A.B.} and Gondrie, {E. T.C.M.} and {de Bruin}, {J. P.}",
note = "Funding Information: We would like to thank the women who participated in this study. We thank all participating hospitals and their staff for their contribution to this study, and the LIFEstyle coaches and research nurses, research midwives, and office members of the Dutch Consortium 2.0 (http://www.studies-obsgyn.nl) for their hard work and dedication. We would like to acknowledge Mrs. A. Bolster (University Medical Center Groningen) as senior trainer of the intervention coaches. Group authorship of The LIFEstyle study group: in addition to the listed authors, J. M. Burggraaff (Scheper Ziekenhuis, Emmen), W. K. H. Kuchenbecker (Isala, Zwolle), D. A. M. Perquin (Medisch Centrum Leeuwarden, Leeuwarden), C. A. M. Koks (Maxima Medisch Centrum, Veldhoven), R. van Golde (Maastricht Universitair Medisch Centrum, Maastricht), E. M. Kaaijk (OLVG, Amsterdam), J.M. Schierbeek (Deventer Ziekenhuis, Deventer), G. J. E. Oosterhuis (St. Antonius Ziekenhuis, Nieuwegein), F. J. Broekmans (Universitair Medisch Centrum Utrecht, Utrecht), N. E. A. Vogel (Martini Ziekenhuis, Groningen), C. B. Lambalk (VU medisch centrum, Amsterdam), F. van der Veen (Academisch Medisch Centrum, Amsterdam), N. F. Klijn (Leiden Universitair Medisch Centrum, Leiden), P. E. A. M. Mercelina (Atrium Medisch Centrum, Heerlen) , Y. M. van Kasteren (Noordwest Ziekenhuisgroep, Alkmaar), A. W. Nap (Rijnstate Ziekenhuis, Arnhem), R. J. A. B. Mulder (Laurentius Ziekenhuis, Roermond), E. T. C. M. Gondrie (Zuyderland Medisch Centrum, Sittard), and J. P. de Bruin (Jeroen Bosch Ziekenhuis, Den Bosch) are members of the LIFEstyle study group and collaborated on this study. Funding Information: Funding The LIFEstyle study was supported by a grant from ZonMw (Prevention program—Health Care Efficiency Research; Project number 50-50110-96-518). This work was funded by the Dutch Heart Foundation (2013T085) and the European Commission (Horizon2020 project 633595 DynaHealth). Neither ZonMw nor the Dutch Heart Foundation nor the European Commission had a role in data collection, analysis, interpretation of data, or writing the report. Funding Information: the UMCG received an unrestricted educational grant from Ferring pharmaceuticals BV, The Netherlands. AvO declares a reimbursement for travel expenses from Ferring BV, outside the submitted work. BWJM is a consultant for ObsEva, Geneva. AH received grants from MSD, pharmaceutical company, grants from Ferring BV, pharmaceutical company, outside the submitted work. The remaining authors have nothing to disclose. Publisher Copyright: {\textcopyright} 2018, The Author(s).",
year = "2019",
month = sep,
day = "1",
doi = "https://doi.org/10.1007/s00394-018-1798-7",
language = "English",
volume = "58",
pages = "2463--2475",
journal = "European Journal of Nutrition",
issn = "1436-6207",
publisher = "D. Steinkopff-Verlag",
number = "6",
}