Diagnostic and therapeutic management of upper extremity deep vein thrombosis

Floris T. M. Bosch, Marcello di Nisio, Harry R. Büller, Nick van Es

Research output: Contribution to journalReview articleAcademicpeer-review

25 Citations (Scopus)

Abstract

Upper extremity deep vein thrombosis (UEDVT) accounts for 5% of all deep vein thromboses (DVTs). UEDVT may be complicated by post thrombotic syndrome and pulmonary embolism, and early recognition and prompt start of anticoagulant treatment are key. Primary UEDVT, also known as Paget-von Schrötter syndrome, is associated with repeated or sudden physical activity of the upper arm and venous outflow obstruction due to anatomical variations. Secondary UEDVT is often associated with malignancy or use of intravenous devices, such as central venous catheters or pacemaker leads. Although the diagnosis and treatment of UEDVT have many similarities with DVT of the lower extremities, knowledge of specific aspects regarding UEDVT is important to guide optimal management. In this review, we will discuss the epidemiology, diagnosis, and treatment of UEDVT based on the current literature.
Original languageEnglish
Pages (from-to)1-14
JournalJournal of clinical medicine
Volume9
Issue number7
DOIs
Publication statusPublished - 1 Jul 2020

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