@article{f942da400b0a42d38a2616764269f703,
title = "Differences in hospitalisation between peritoneal dialysis and haemodialysis patients",
abstract = "BACKGROUND: Dialysis is associated with frequent hospitalisations. Studies comparing hospitalisations between peritoneal dialysis (PD) and haemodialysis (HD) report conflicting results and mostly analyse data of patients that remain on their initial dialysis modality. This cohort study compares hospitalisations between PD and HD patients taking into account transitions between modalities. METHODS: The Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes collected hospitalisation data of patients who started dialysis between 2012 and 2017. Primary outcome was hospitalisation rate, analysed with a multi-state model that attributed each hospitalisation to the current dialysis modality. RESULTS: In total, 695 patients (252 PD, 443 HD) treated in 31 Dutch hospitals were included. The crude hospitalisation rate for PD was 2.3 ( ± 5.0) and for HD 1.4 ( ± 3.2) hospitalisations per patient-year. The adjusted hazard ratio for hospitalisation rate was 1.1 (95%CI 1.02-1.3) for PD compared with HD. The risk for first hospitalisation was 1.3 times (95%CI 1.1-1.6) higher for PD compared with HD during the first year after dialysis initiation. The number of hospitalisations and number of hospital days per patient-year were significantly higher for PD. The most common causes of PD and HD hospitalisations were peritonitis (23%) and vascular access-related problems (33%). CONCLUSION: PD was associated with higher hospitalisation rate, higher risk for first hospitalisation and higher number of hospitalisations compared with HD. Since the PD hospitalisations were mainly caused by peritonitis, more attention to infection prevention is necessary for reducing the number of hospitalisations in the future.",
keywords = "end-stage kidney disease, haemodialysis, hospitalisation, peritoneal dialysis",
author = "{van Eck van der Sluijs}, Anita and Bonenkamp, {Anna A.} and {van Wallene}, {Vera A.} and Tiny Hoekstra and Lissenberg-Witte, {Birgit I.} and Dekker, {Friedo W.} and {van Ittersum}, {Frans J.} and Verhaar, {Marianne C.} and {DOMESTICO study group} and {van Jaarsveld}, {Brigit C.} and Abrahams, {Alferso C.} and {the DOMESTICO study group} and Struijk, {D. G.} and Boereboom, {F. T. J.} and W. Konijn and Vermeeren, {Y. M.} and Hemmelder, {M. H.} and {ten Dam}, {M. A. G. J.} and {de Fijter}, {C. W. H.} and S. Vonk and Korte, {M. R.} and Cnossen, {T. T.} and Krepel, {H. P.} and {ten Dam}, {M. A. G. J.} and Konings, {C. J. A. M.} and Doorenbos, {C. J.} and A. Lips and A. {\"O}zyilmaz and Struijk, {D. G.} and Boereboom, {F. T. J.} and {van Esch}, S. and {van Breda}, {G. F.} and Hoorn, {E. J.} and D. Severs and Boonstra, {A. H.} and Nette, {R. W.} and Vermeeren, {Y. M.} and Thang, {H. D.} and Hommes, {N. H.} and {van Buren}, M. and Hofstra, {J. M.} and Diepeveen, {S. H. A.} and S. Boorsma and Rotmans, {J. I.} and {van der Sande}, F. and Litjens, {E. J. R.} and Brink, {H. S.} and R. Wijering and Hagen, {E. C.} and Penne, {E. L.} and {de Fijter}, {C. W. H.} and Brulez, {H. F. H.}",
note = "Funding Information: The retrospective part of the {\textquoteleft}Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes{\textquoteright} is supported by a grant of the Dutch Kidney Foundation (Grant no: A2D4P02). The sponsor had no role in the design and conduct of the study and no role in writing or in the decision to publish this paper. Funding Information: The retrospective part of the {\textquoteleft}Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes{\textquoteright} is supported by a grant of the Dutch Kidney Foundation (Grant no: A2D4P02). The sponsor had no role in the design and conduct of the study and no role in writing or in the decision to publish this paper. We would like to thank all participating patients and dialysis centres of the DOMESTICO study. DOMESTICO committee members: AA Bonenkamp and FJ van Ittersum, Amsterdam University Medical Centres; BC van Jaarsveld, Amsterdam University Medical Centres and Diapriva Dialysis Centre Amsterdam; DG Struijk and FTJ Boereboom, Dianet Amsterdam-Utrecht; W Konijn, Dutch Kidney Patients Association (NVN); YM Vermeeren, Gelre Hospitals Apeldoorn; FW Dekker, Leiden University Medical Centre; MH Hemmelder, Maastricht UMC+; MAGJ ten Dam, Nefrovisie and Canisius-Wilhelmina Hospital Nijmegen; CWH de Fijter, OLVG Amsterdam; A van Eck van der Sluijs, S Vonk, MC Verhaar and AC Abrahams, University Medical Centre Utrecht. Investigators of the retrospective DOMESTICO study: MR Korte, Albert Schweitzer Hospital Dordrecht; TT Cnossen, Amphia Hospital Breda; BC van Jaarsveld, Amsterdam University Medical Centres and Diapriva Dialysis Centre Amsterdam; HP Krepel, Bravis Hospital Roosendaal; Canisius-Wilhelmina Hospital Nijmegen; CJAM Konings, Catharina Hospital Eindhoven; CJ Doorenbos, Deventer Hospital; A Lips, Dialysis Centre Beverwijk; A {\"O}zyilmaz, Dialysis Centre Groningen; Dianet Amsterdam; Dianet Utrecht; S van Esch, Elisabeth-TweeSteden Hospital Tilburg; GF van Breda, Elyse Clinics; EJ Hoorn and D Severs, Erasmus Medical Centre Rotterdam; AH Boonstra, Flevohospital Almere; RW Nette, Franciscus Gasthuis & Vlietland Rotterdam; Gelre Hospitals Apeldoorn; HD Thang and NH Hommes, Haaglanden Medical Centre The Hague; M van Buren, HagaHospital The Hague; JM Hofstra, Hospital Gelderse Vallei Ede; SHA Diepeveen, Isala Zwolle; S Boorsma, Laurentius Hospital Roermond; JI Rotmans, Leiden University Medical Centre; F van der Sande and EJR Litjens, Maastricht UMC+; HS Brink and R Wijering, Medical Spectrum Twente Enschede; EC Hagen, Niercentrum Midden Nederland Amersfoort; EL Penne, Northwest Clinics Alkmaar; and HFH Brulez, OLVG Amsterdam; HW van Hamersvelt, Radboud UMC Nijmegen; SJ Huisman, Reinier de Graaf Gasthuis Delft; CE Douma, Spaarne Gasthuis Hoofddorp; AC Abrahams, University Medical Centre Utrecht; AJ Luik, VieCuri Medical Centre Venlo; RJL Klaassen, Zaans Medical Centre Zaandam; AG Weenink, ZorgSaam Hospital Terneuzen; MME Krekels, Zuyderland Sittard. Publisher Copyright: {\textcopyright} 2022 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation.",
year = "2022",
month = jun,
day = "1",
doi = "https://doi.org/10.1111/eci.13758",
language = "English",
volume = "52",
pages = "e13758",
journal = "European journal of clinical investigation",
issn = "0014-2972",
publisher = "Wiley-Blackwell Publishing",
number = "6",
}