Discontinuation of intravenous oxytocin in the active phase of induced labour

Sidsel Boie, Julie Glavind, Adeline V. Velu, Ben Willem J. Mol, Niels Uldbjerg, Irene de Graaf, Jim G. Thornton, Pinar Bor, Jannet Jh Bakker

Research output: Contribution to journalReview articleAcademicpeer-review


BACKGROUND: In most Western countries, obstetricians and midwives induce labour in about 25% of pregnant women. Oxytocin is an effective drug for this purpose, but associated with serious adverse effects of which uterine tachysystole, fetal distress and the need for immediate delivery are the most common. Various administration regimens such as reduced or pulsatile dosing have been suggested to minimise these. Discontinuation in the active phase of labour, i.e. when contractions are well-established and the cervix is dilated at least 5 cm is another method which may reduce adverse effects.
Original languageEnglish
Pages (from-to)CD012274
JournalCochrane database of systematic reviews (Online)
Publication statusPublished - 2018

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