Dopamine transporter occupancy by methylphenidate and impulsivity in adult ADHD

Cleo L. Crunelle; Wim van den Brink; Geert Dom; Jan Booij

doi:https://doi.org/10.1192/bjp.bp.113.132977

Dopamine transporter occupancy by methylphenidate and impulsivity in adult ADHD

Cleo L. Crunelle, Wim van den Brink, Geert Dom, Jan Booij

Research output: Contribution to journal › Article › Academic › peer-review

9 Citations (Scopus)

Abstract

Impulsivity is a multidimensional construct, including impulsive decision-making and impulsive action, representing relatively independent neurocircuitries. ADHD is treated with methylphenidate, a drug that binds to dopamine transporters. This study in 24 adult male patients with ADHD shows that dopamine transporter occupancy by methylphenidate in the putamen correlates with improvements in cognitive but not in motor impulsivity

Original language	English
Pages (from-to)	486-487
Journal	British journal of psychiatry
Volume	204
Issue number	6
DOIs	https://doi.org/10.1192/bjp.bp.113.132977
Publication status	Published - 2014

Access to Document

https://doi.org/10.1192/bjp.bp.113.132977

Cite this

@article{520b5f44933a4a62b325acc2de415a7a,

title = "Dopamine transporter occupancy by methylphenidate and impulsivity in adult ADHD",

abstract = "Impulsivity is a multidimensional construct, including impulsive decision-making and impulsive action, representing relatively independent neurocircuitries. ADHD is treated with methylphenidate, a drug that binds to dopamine transporters. This study in 24 adult male patients with ADHD shows that dopamine transporter occupancy by methylphenidate in the putamen correlates with improvements in cognitive but not in motor impulsivity",

author = "Crunelle, {Cleo L.} and {van den Brink}, Wim and Geert Dom and Jan Booij",

year = "2014",

doi = "https://doi.org/10.1192/bjp.bp.113.132977",

language = "English",

volume = "204",

pages = "486--487",

journal = "British journal of psychiatry",

issn = "0007-1250",

publisher = "Royal College of Psychiatrists",

number = "6",

}

TY - JOUR

T1 - Dopamine transporter occupancy by methylphenidate and impulsivity in adult ADHD

AU - Crunelle, Cleo L.

AU - van den Brink, Wim

AU - Dom, Geert

AU - Booij, Jan

PY - 2014

Y1 - 2014

N2 - Impulsivity is a multidimensional construct, including impulsive decision-making and impulsive action, representing relatively independent neurocircuitries. ADHD is treated with methylphenidate, a drug that binds to dopamine transporters. This study in 24 adult male patients with ADHD shows that dopamine transporter occupancy by methylphenidate in the putamen correlates with improvements in cognitive but not in motor impulsivity

AB - Impulsivity is a multidimensional construct, including impulsive decision-making and impulsive action, representing relatively independent neurocircuitries. ADHD is treated with methylphenidate, a drug that binds to dopamine transporters. This study in 24 adult male patients with ADHD shows that dopamine transporter occupancy by methylphenidate in the putamen correlates with improvements in cognitive but not in motor impulsivity

U2 - https://doi.org/10.1192/bjp.bp.113.132977

DO - https://doi.org/10.1192/bjp.bp.113.132977

M3 - Article

C2 - 24676965

SN - 0007-1250

VL - 204

SP - 486

EP - 487

JO - British journal of psychiatry

JF - British journal of psychiatry

IS - 6

ER -