Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Eline Houben; Pieter F. de Groot; Yosta Vegting; Josephine M. I. Vos; Erfan Nur; Marc L. Hilhorst; A. E. Hak; Arjan J. Kwakernaak

doi:https://doi.org/10.3390/jcm12196144

Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Eline Houben, Pieter F. de Groot, Yosta Vegting, Josephine M. I. Vos, Erfan Nur, Marc L. Hilhorst, A. E. Hak, Arjan J. Kwakernaak

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare heterogeneous disease in which treatment must be initiated early to prevent irreversible organ damage and death. There are several diseases that can mimic AAV, even in the presence of positive ANCA serology and/or histological evidence of vasculitis, as demonstrated in this case series. We reflect on the diagnostic approach of patients with AAV and provide an overview of AAV-mimicking diseases that can be considered in patients with atypical disease presentation or course.

Original language	English
Article number	6144
Journal	Clinical Chemistry
Volume	12
Issue number	19
DOIs	https://doi.org/10.3390/jcm12196144
Publication status	Published - 1 Oct 2023

Keywords

ANCA-associated vasculitis
NK/T-cell lymphoma
cryoglobulinemic vasculitis
mimicking disease
mycobacterium avium complex

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abstract = "Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare heterogeneous disease in which treatment must be initiated early to prevent irreversible organ damage and death. There are several diseases that can mimic AAV, even in the presence of positive ANCA serology and/or histological evidence of vasculitis, as demonstrated in this case series. We reflect on the diagnostic approach of patients with AAV and provide an overview of AAV-mimicking diseases that can be considered in patients with atypical disease presentation or course.",

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AU - Vos, Josephine M. I.

AU - Nur, Erfan

AU - Hilhorst, Marc L.

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AB - Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare heterogeneous disease in which treatment must be initiated early to prevent irreversible organ damage and death. There are several diseases that can mimic AAV, even in the presence of positive ANCA serology and/or histological evidence of vasculitis, as demonstrated in this case series. We reflect on the diagnostic approach of patients with AAV and provide an overview of AAV-mimicking diseases that can be considered in patients with atypical disease presentation or course.

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KW - NK/T-cell lymphoma

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Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Abstract

Keywords

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