TY - JOUR
T1 - Whole-liver flip-angle shimming at 7 T using parallel-transmit kT-point pulses and Fourier phase-encoded DREAM B1+ mapping
AU - Runderkamp, Bobby A.
AU - Roos, Thomas
AU - van der Zwaag, Wietske
AU - Strijkers, Gustav J.
AU - Caan, Matthan W. A.
AU - Nederveen, Aart J.
N1 - Publisher Copyright: © 2023 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.
PY - 2024/1
Y1 - 2024/1
N2 - Purpose: To obtain homogeneous signal throughout the human liver at 7 T. Flip angle (FA) shimming in 7T whole-liver imaging was performed through parallel-transmit kT-point pulses based on subject-specific multichannel absolute (Formula presented.) maps from Fourier phase-encoded dual refocusing echo acquisition mode (PE-DREAM). Methods: The optimal number of Fourier phase-encoding steps for PE-DREAM (Formula presented.) mapping was determined for a 7T eight-channel parallel-transmission system. FA shimming experiments were performed in the liver of 7 healthy subjects with varying body mass index. In these subjects, first (Formula presented.) shimming and Fourier PE-DREAM (Formula presented.) mapping were performed. Subsequently, three small-flip-angle 3D gradient-echo scans were acquired, comparing a circularly polarized (CP) mode, a phase shim, and a kT-point pulse. Resulting homogeneity was assessed and compared with estimated FA maps and distributions. Results: Fourier PE-DREAM with 13 phase-encoding steps resulted in a good tradeoff between (Formula presented.) accuracy and scan time. Lower coefficient of variation values (average [min-max] across subjects) of the estimated FA in the volume of interest were observed using kT-points (7.4 [6.6%–8.0%]), compared with phase shimming (18.8 [12.9%–23.4%], p < 0.001) and CP (43.2 [39.4%–47.1%], p < 0.001). kT-points delivered whole-liver images with the nominal FA and the highest degree of homogeneity. CP and phase shimming resulted in either inaccurate or imprecise FA distributions. Here, locations having suboptimal FA in the estimated FA maps corresponded to liver areas suffering from inconsistent signal intensity and T1-weighting in the gradient-echo scans. Conclusion: Homogeneous whole-liver 3D gradient-echo acquisitions at 7 T can be obtained with eight-channel kT-point pulses calculated based on subject-specific multichannel absolute Fourier PE-DREAM (Formula presented.) maps.
AB - Purpose: To obtain homogeneous signal throughout the human liver at 7 T. Flip angle (FA) shimming in 7T whole-liver imaging was performed through parallel-transmit kT-point pulses based on subject-specific multichannel absolute (Formula presented.) maps from Fourier phase-encoded dual refocusing echo acquisition mode (PE-DREAM). Methods: The optimal number of Fourier phase-encoding steps for PE-DREAM (Formula presented.) mapping was determined for a 7T eight-channel parallel-transmission system. FA shimming experiments were performed in the liver of 7 healthy subjects with varying body mass index. In these subjects, first (Formula presented.) shimming and Fourier PE-DREAM (Formula presented.) mapping were performed. Subsequently, three small-flip-angle 3D gradient-echo scans were acquired, comparing a circularly polarized (CP) mode, a phase shim, and a kT-point pulse. Resulting homogeneity was assessed and compared with estimated FA maps and distributions. Results: Fourier PE-DREAM with 13 phase-encoding steps resulted in a good tradeoff between (Formula presented.) accuracy and scan time. Lower coefficient of variation values (average [min-max] across subjects) of the estimated FA in the volume of interest were observed using kT-points (7.4 [6.6%–8.0%]), compared with phase shimming (18.8 [12.9%–23.4%], p < 0.001) and CP (43.2 [39.4%–47.1%], p < 0.001). kT-points delivered whole-liver images with the nominal FA and the highest degree of homogeneity. CP and phase shimming resulted in either inaccurate or imprecise FA distributions. Here, locations having suboptimal FA in the estimated FA maps corresponded to liver areas suffering from inconsistent signal intensity and T1-weighting in the gradient-echo scans. Conclusion: Homogeneous whole-liver 3D gradient-echo acquisitions at 7 T can be obtained with eight-channel kT-point pulses calculated based on subject-specific multichannel absolute Fourier PE-DREAM (Formula presented.) maps.
KW - 7 T
KW - Fourier phase-encoded DREAM
KW - flip-angle shimming
KW - k-points
KW - liver
KW - parallel transmission
UR - http://www.scopus.com/inward/record.url?scp=85173530482&partnerID=8YFLogxK
U2 - https://doi.org/10.1002/mrm.29819
DO - https://doi.org/10.1002/mrm.29819
M3 - Article
C2 - 37799015
SN - 0740-3194
VL - 91
SP - 75
EP - 90
JO - Magnetic resonance in medicine
JF - Magnetic resonance in medicine
IS - 1
ER -