Electric Field Modeling for Transcranial Magnetic Stimulation and Electroconvulsive Therapy

Zhi-De Deng, Conor Liston, Faith M. Gunning, Marc J. Dubin, Egill Axfjörđ Fridgeirsson, Joseph Lilien, Guido van Wingen, Jeroen van Waarde

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

11 Citations (Scopus)

Abstract

Major depressive disorder (MDD) is a highly prevalent condition and present first-line treatment options are inadequate. Among nonpharmacological treatment alternatives, noninvasive brain stimulation shows tremendous promise. There are two approved brain stimulation techniques for the treatment of MDD: electroconvulsive therapy (ECT) and repetitive transcranial magnetic stimulation (rTMS). The goal of this study is to quantify the induced electric field (E-field) at the dorsolateral prefrontal cortex (DLPFC) in a group of depressed patients. This study aimed to characterize the induced electric field distributions in a population of patients who received bilateral and/or unilateral electroconvulsive therapy and in a group of patients who received rTMS for the treatment of depression. We also investigated an alternative magnetic stimulation approach, using rotating permanent magnets.
Original languageEnglish
Title of host publicationBrain and Human Body Modeling: Computational Human Modeling at EMBC 2018
EditorsS. Makarov, M. Horner, G. Noetscher
PublisherSpringer International Publishing
Chapter4
Pages75-84
ISBN (Electronic)9783030212933
ISBN (Print)9783030212926
DOIs
Publication statusPublished - 1 Jan 2019

Publication series

NameBrain and Human Body Modeling: Computational Human Modeling at EMBC 2018

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