TY - JOUR
T1 - Endocarditis Caused by Nontypeable Streptococcus pneumoniae
AU - Henriet, Stefanie S. V.
AU - Langereis, Jeroen D.
AU - Lo, Stephanie W.
AU - Bentley, Stephen
AU - Mesman, Rob J.
AU - Fejzic, Zina
AU - van Niftrik, Laura
AU - van Sorge, Nina M.
AU - Wertheim, Heiman F. L.
AU - de Jonge, Marien I.
AU - Cremers, Amelieke J. H.
N1 - Publisher Copyright: © The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America.
PY - 2022/9/10
Y1 - 2022/9/10
N2 - The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.
AB - The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.
KW - Streptococcus pneumoniae
KW - bacterial polysaccharide capsule
KW - infective endocarditis
KW - pathogenesis
UR - http://www.scopus.com/inward/record.url?scp=85138128982&partnerID=8YFLogxK
U2 - https://doi.org/10.1093/cid/ciac079
DO - https://doi.org/10.1093/cid/ciac079
M3 - Article
C2 - 35134152
SN - 1058-4838
VL - 75
SP - 719
EP - 722
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 4
ER -