Endovascular aneurysm closure during out of office hours is not related to complications or outcome

Jasper H. van Lieshout, Dagmar Verbaan, Igor Fischer, Hendrik Jan Mijderwijk, René van den Berg, W. Peter Vandertop, Catharina J.M. Klijn, Hans J. Steiger, Joost de Vries, Ronald H.M.A. Bartels, Kerim Beseoglu, Hieronymus D. Boogaarts

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)


Purpose: A possible disadvantage of endovascular occlusion outside work hours is that complex procedures might expose patients to additional risk when performed in a suboptimal setting. In this prospective cohort study, we evaluated whether treatment during out of office hours is a risk factor for per-procedural complications and clinical outcome. Methods: We included 471 endovascular-treated, consecutive aneurysmal subarachnoid hemorrhage patients (56.6 ± 13.1, 69% female), from two prospective observational databases which were retrospectively analyzed. Primary outcome was the occurrence of per-procedural complications. Secondary outcomes were good clinical outcome (modified ranking scale ≤ 2) and death at 6-month follow-up. We determined odds ratios (OR) with 95% confidence intervals (CI) by ordered polytomous logistic regression analysis and adjusted odds ratios (aOR) for age, World Federation of Neurosurgical Societies grade, and time to treatment. Results: Most patients were treated during office hours (363/471; 77.1%). Treatment during out of office hours did not result in an increased risk of per-procedural complications (OR 0.85 (95% CI 0.53–1.37; p = 0.51). Patients treated during out of office hours displayed similar odds of good clinical outcome and death after 6 months (OR 1.14, 95% CI 0.68–1.97 and 1.16 95% CI 0.56–2.29, respectively) compared to patients treated during office hours. Conclusion: In our study, endovascular coil embolization during out of office hours did not expose patients to an increased risk of procedural complications or affect functional outcome after 6 months.

Original languageEnglish
Pages (from-to)741-746
Number of pages6
Issue number6
Early online date7 Feb 2020
Publication statusPublished - 1 Jun 2020


  • Aneurysmal subarachnoid hemorrhage
  • Cohort study
  • Outcome research
  • Patient safety
  • Risk factors in epidemiology

Cite this