Estimation of macular pigment optical density in the elderly: test-retest variability and effect of optical blur in pseudophakic subjects

Kevin T. Gallaher, Marco Mura, Wm Andrew Todd, Tarsha L. Harris, Emily Kenyon, Tamara Harris, Karen C. Johnson, Suzanne Satterfield, Stephen B. Kritchevsky, Alessandro Iannaccone

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Abstract

The reproducibility of macular pigment optical density (MPOD) estimates in the elderly was assessed in 40 subjects (age: 79.1+/-3.5). Test-retest variability was good (Pearson's r coefficient: 0.734), with an average coefficient of variation (CV) of 18.4% and an intraclass correlation coefficient (ICC) of 0.96. The effect of optical blur on MPOD estimates was investigated in 22 elderly pseudophakic subjects (age: 79.9+/-3.6) by comparing the baseline MPOD, obtained with an optimal correction, with MPODs obtained with a +/-1.00-diopter optical blur. This optical blur did not cause differences in the MPOD estimates, its accuracy, or test duration
Original languageEnglish
Pages (from-to)1253-1259
JournalVision research
Volume47
Issue number9
DOIs
Publication statusPublished - 2007

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