European Association of Urology Section of Urolithiasis and International Alliance of Urolithiasis Joint Consensus on Retrograde Intrarenal Surgery for the Management of Renal Stones

Guohua Zeng, Zhijian Zhao, Giorgio Mazzon, Margaret Pearle, Simon Choong, Andreas Skolarikos, John Denstedt, Christian Seitz, Daniel Olvera Pasada, Cristian Fiori, Adrea Bosio, Athanasios Papatsoris, Carlos Enrique Méndez Probst, Daniel Perez Fentes, Kah Ann Git, Qinghui Wu, Oliver Wiseman, Esteban Emiliani, Yasser Farahat, Mehmet Ilker GökceStilianos Giannakopoulos, Ioannis Goumas Kartalas, Bhaskar Somani, Thomas Knoll, Jean de la Rosette, Jiehui Zhong, Marcus Vinicius Maroccolo, lliya Saltirov, Ben Chew, Kunjie Wang, Sven Lahme, Guido Giusti, Stefania Ferretti, Sung Yong Cho, Petrisor Geavlete, Ramon Cansino, Guido M. Kamphuis, Daron Smith, Brian R. Matlaga, Khurshid D. Ghani, Norberto Bernardo, Andres D. Silva, Anthony C. F. Ng, Sixing Yang, Xiaofeng Gao, Olivier Traxer, Arkadiusz Miernik, Evangelos Liatsikos, Kandarp Priyakant Parikh, Mordechai Duvdevani, Antonio Celia, Takahiro Yasui, Albert Aquino, Mohammad Alomar, Vorapot Choonhaklai, Bulent Erkurt, Jonathan Glass, Seshadri Sriprasad, Palle J. Osther, Francis X. Keeley, Glenn M. Preminger, Marcos Cepeda Delgado, Edgar Beltran Suarez, Zhangqun Ye, Kemal Sarica

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)


Background: Retrograde intrarenal surgery (RIRS) has become the preferred treatment modality for nephrolithiasis. However, because of ongoing uncertainties regarding the optimal perioperative management, operative technique, and postoperative follow-up, as well as a lack of standardization for outcome reporting, consensus is needed to achieve more uniform clinical practice worldwide. Objective: To develop recommendations for RIRS on the basis of existing data and expert consensus. Design, setting, and participants: A protocol-driven, three-phase study was conducted by the European Association of Urology Section of Urolithiasis (EULIS) and the International Alliance of Urolithiasis (IAU). The process included: (1) a nonsystematic review of the literature to define domains for discussion; (2) a two-round modified Delphi survey involving experts in this field; and (3) an additional group meeting and third-round survey involving 64 senior representative members to formulate the final conclusions. Outcome measurements and statistical analysis: The results from each previous round were returned to the participants for re-evaluation of their decisions during the next round. The agreement threshold was set at 70%. Results and limitations: The panel included 209 participants who developed 29 consensus statements on the following topics of interest: (1) perioperative infection management; (2) perioperative antithrombotic therapy; (3) fundamentals of the operative technique; and (4) standardized outcome reporting. Although this consensus can be considered as a useful reference for more clinically oriented daily practice, we also acknowledge that a higher level of evidence from further clinical trials is needed. Conclusions: The consensus statements aim to guide and standardize clinical practice and research on RIRS and to recommend standardized outcome reporting. Patient summary: An international consensus on the best practice for minimally invasive surgery for kidney stones was organized and developed by two international societies. It is anticipated that this consensus will provide further guidance to urologists and may help to improve clinical outcomes for patients.
Original languageEnglish
Pages (from-to)1461-1468
Number of pages8
JournalEuropean Urology Focus
Issue number5
Early online date2021
Publication statusPublished - Sept 2022


  • Delphi process
  • Expert consensus
  • Retrograde intrarenal surgery

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