TY - JOUR
T1 - Evaluating the risks of arrhythmia through big data
T2 - 44th Computing in Cardiology Conference, CinC 2017
AU - Ledezma, Carlos A.
AU - Kappler, Benjamin
AU - Meijborg, Veronique
AU - Boukens, Bas
AU - Stijnen, Marco
AU - Tan, P. J.
AU - Díaz-Zuccarini, Vanessa
N1 - Funding Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 642612, VPH-CaSE (www.vph-case.eu) Publisher Copyright: © 2017 IEEE Computer Society. All rights reserved.
PY - 2017
Y1 - 2017
N2 - Arrhythmic behaviors are a major risk to the population. These are diverse and can have their origin in cellular dynamics that affect the functioning of the heart. When trying to understand the mechanisms behind arrhythmogenesis the epicardial electrograms present themselves as a useful measurement because they reflect the electrical behavior of the cells surrounding the electrodes. Nevertheless, there is a lack of methods in the literature to automatically process and analyze these signals. In this paper, an algorithm to automatically detect the R, S and T wave peaks in epicardial electrogram signals is presented. This algorithm uses the derivative of the signal to find the activation and recovery times, and uses these as fiducial points to find the desired features. These features are then used as inputs to an artificial neural network, trained to classify individual beats into 'healthy' and 'pathological'. After optimization, both the detector and the neural network showed good performance in their tasks; furthermore, the robustness and amenability to real-time implementation of the methods here presented make them ideal for monitoring patients or experimental platforms when epicardial electrograms can be measured.
AB - Arrhythmic behaviors are a major risk to the population. These are diverse and can have their origin in cellular dynamics that affect the functioning of the heart. When trying to understand the mechanisms behind arrhythmogenesis the epicardial electrograms present themselves as a useful measurement because they reflect the electrical behavior of the cells surrounding the electrodes. Nevertheless, there is a lack of methods in the literature to automatically process and analyze these signals. In this paper, an algorithm to automatically detect the R, S and T wave peaks in epicardial electrogram signals is presented. This algorithm uses the derivative of the signal to find the activation and recovery times, and uses these as fiducial points to find the desired features. These features are then used as inputs to an artificial neural network, trained to classify individual beats into 'healthy' and 'pathological'. After optimization, both the detector and the neural network showed good performance in their tasks; furthermore, the robustness and amenability to real-time implementation of the methods here presented make them ideal for monitoring patients or experimental platforms when epicardial electrograms can be measured.
UR - http://www.scopus.com/inward/record.url?scp=85045085878&partnerID=8YFLogxK
U2 - https://doi.org/10.22489/CinC.2017.209-269
DO - https://doi.org/10.22489/CinC.2017.209-269
M3 - Article
SN - 2325-8861
VL - 44
SP - 1
EP - 4
JO - Computing in Cardiology
JF - Computing in Cardiology
Y2 - 24 September 2017 through 27 September 2017
ER -