Ideal cardiovascular health and cardiovascular related events: a systematic review and meta-analysis

Femke Te Hoonte; Merve Spronk; Qi Sun; Kangrui Wu; Shiqi Fan; Ziyi Wang; Michiel L Bots; Yvonne T Van der Schouw; Alicia Uijl; Robin W M Vernooij

doi:https://doi.org/10.1093/eurjpc/zwad405

Ideal cardiovascular health and cardiovascular related events: a systematic review and meta-analysis

Femke Te Hoonte, Merve Spronk, Qi Sun, Kangrui Wu, Shiqi Fan, Ziyi Wang, Michiel L Bots, Yvonne T Van der Schouw, Alicia Uijl, Robin W M Vernooij

Cardiology (AMC)

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

AIMS: The aim of this study was to systematically review and quantitatively summarise the evidence on the association between Life Simple's 7 (LS7) and multiple cardiovascular diseases (CVD) and cardiometabolic diseases (CMD).

METHODS: EMBASE and PubMed were searched from January 2010 to March 2022 for observational studies that investigated the association between ideal cardiovascular health (CVH) with CVD or CMD outcomes in an adult population. Two reviewers independently selected studies according to the eligibility criteria, extracted data, and evaluated risk of bias. Data were analysed with a random-effect meta-analysis.

RESULTS: This meta-analysis included 59 studies (1,881,382 participants). Participants with ideal CVH had a considerably lower risk of a variety of CVDs and CMDs as compared to those with poor CVH, varying from 40% lower risk for atrial fibrillation (AF) (HR = 0.60 [95% CI 0.44-0.83]) to 82% lower risk for myocardial infarction (HR = 0.18 [95% CI 0.12-0.28]). Intermediate CVH was associated with 27%-57% lower risk in CVDs and CMDs compared to poor CVH, with the highest hazard for AF (HR = 0.73 [95% CI 0.59-0.91]), and the lowest hazard for peripheral arterial disease (HR = 0.43 [95% CI 0.30-0.60]).

CONCLUSION: Ideal and moderate CVH were associated with a lower incidence of CVDs and CMDs than poor CVH. LS7 holds significant potential for promoting overall CVH and thereby contributing to the prevention of CVDs.

Original language	English
Journal	European journal of preventive cardiology
DOIs	https://doi.org/10.1093/eurjpc/zwad405
Publication status	E-pub ahead of print - 27 Dec 2023

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https://doi.org/10.1093/eurjpc/zwad405

Cite this

@article{f4f343d8deb444d28520706f27ff2911,

title = "Ideal cardiovascular health and cardiovascular related events: a systematic review and meta-analysis",

abstract = "AIMS: The aim of this study was to systematically review and quantitatively summarise the evidence on the association between Life Simple's 7 (LS7) and multiple cardiovascular diseases (CVD) and cardiometabolic diseases (CMD).METHODS: EMBASE and PubMed were searched from January 2010 to March 2022 for observational studies that investigated the association between ideal cardiovascular health (CVH) with CVD or CMD outcomes in an adult population. Two reviewers independently selected studies according to the eligibility criteria, extracted data, and evaluated risk of bias. Data were analysed with a random-effect meta-analysis.RESULTS: This meta-analysis included 59 studies (1,881,382 participants). Participants with ideal CVH had a considerably lower risk of a variety of CVDs and CMDs as compared to those with poor CVH, varying from 40% lower risk for atrial fibrillation (AF) (HR = 0.60 [95% CI 0.44-0.83]) to 82% lower risk for myocardial infarction (HR = 0.18 [95% CI 0.12-0.28]). Intermediate CVH was associated with 27%-57% lower risk in CVDs and CMDs compared to poor CVH, with the highest hazard for AF (HR = 0.73 [95% CI 0.59-0.91]), and the lowest hazard for peripheral arterial disease (HR = 0.43 [95% CI 0.30-0.60]).CONCLUSION: Ideal and moderate CVH were associated with a lower incidence of CVDs and CMDs than poor CVH. LS7 holds significant potential for promoting overall CVH and thereby contributing to the prevention of CVDs.",

author = "{Te Hoonte}, Femke and Merve Spronk and Qi Sun and Kangrui Wu and Shiqi Fan and Ziyi Wang and Bots, {Michiel L} and {Van der Schouw}, {Yvonne T} and Alicia Uijl and Vernooij, {Robin W M}",

note = "{\textcopyright} The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.",

year = "2023",

month = dec,

day = "27",

doi = "https://doi.org/10.1093/eurjpc/zwad405",

language = "English",

journal = "European journal of preventive cardiology",

issn = "2047-4873",

publisher = "SAGE Publications Ltd",

}

TY - JOUR

T1 - Ideal cardiovascular health and cardiovascular related events

T2 - a systematic review and meta-analysis

AU - Te Hoonte, Femke

AU - Spronk, Merve

AU - Sun, Qi

AU - Wu, Kangrui

AU - Fan, Shiqi

AU - Wang, Ziyi

AU - Bots, Michiel L

AU - Van der Schouw, Yvonne T

AU - Uijl, Alicia

AU - Vernooij, Robin W M

PY - 2023/12/27

Y1 - 2023/12/27

N2 - AIMS: The aim of this study was to systematically review and quantitatively summarise the evidence on the association between Life Simple's 7 (LS7) and multiple cardiovascular diseases (CVD) and cardiometabolic diseases (CMD).METHODS: EMBASE and PubMed were searched from January 2010 to March 2022 for observational studies that investigated the association between ideal cardiovascular health (CVH) with CVD or CMD outcomes in an adult population. Two reviewers independently selected studies according to the eligibility criteria, extracted data, and evaluated risk of bias. Data were analysed with a random-effect meta-analysis.RESULTS: This meta-analysis included 59 studies (1,881,382 participants). Participants with ideal CVH had a considerably lower risk of a variety of CVDs and CMDs as compared to those with poor CVH, varying from 40% lower risk for atrial fibrillation (AF) (HR = 0.60 [95% CI 0.44-0.83]) to 82% lower risk for myocardial infarction (HR = 0.18 [95% CI 0.12-0.28]). Intermediate CVH was associated with 27%-57% lower risk in CVDs and CMDs compared to poor CVH, with the highest hazard for AF (HR = 0.73 [95% CI 0.59-0.91]), and the lowest hazard for peripheral arterial disease (HR = 0.43 [95% CI 0.30-0.60]).CONCLUSION: Ideal and moderate CVH were associated with a lower incidence of CVDs and CMDs than poor CVH. LS7 holds significant potential for promoting overall CVH and thereby contributing to the prevention of CVDs.

AB - AIMS: The aim of this study was to systematically review and quantitatively summarise the evidence on the association between Life Simple's 7 (LS7) and multiple cardiovascular diseases (CVD) and cardiometabolic diseases (CMD).METHODS: EMBASE and PubMed were searched from January 2010 to March 2022 for observational studies that investigated the association between ideal cardiovascular health (CVH) with CVD or CMD outcomes in an adult population. Two reviewers independently selected studies according to the eligibility criteria, extracted data, and evaluated risk of bias. Data were analysed with a random-effect meta-analysis.RESULTS: This meta-analysis included 59 studies (1,881,382 participants). Participants with ideal CVH had a considerably lower risk of a variety of CVDs and CMDs as compared to those with poor CVH, varying from 40% lower risk for atrial fibrillation (AF) (HR = 0.60 [95% CI 0.44-0.83]) to 82% lower risk for myocardial infarction (HR = 0.18 [95% CI 0.12-0.28]). Intermediate CVH was associated with 27%-57% lower risk in CVDs and CMDs compared to poor CVH, with the highest hazard for AF (HR = 0.73 [95% CI 0.59-0.91]), and the lowest hazard for peripheral arterial disease (HR = 0.43 [95% CI 0.30-0.60]).CONCLUSION: Ideal and moderate CVH were associated with a lower incidence of CVDs and CMDs than poor CVH. LS7 holds significant potential for promoting overall CVH and thereby contributing to the prevention of CVDs.

U2 - https://doi.org/10.1093/eurjpc/zwad405

DO - https://doi.org/10.1093/eurjpc/zwad405

M3 - Article

C2 - 38149986

SN - 2047-4873

JO - European journal of preventive cardiology

JF - European journal of preventive cardiology

ER -