Facial clefts and associated limb anomalies: description of three cases and a review of the literature

M. C. Obdeijn, P. J. Offringa, R. R. M. Bos, A. A. E. Verhagen, F. B. Niessen, N. A. Roche

Research output: Contribution to journalReview articleAcademicpeer-review

10 Citations (Scopus)


Facial clefts are rare congenital malformations. In the literature these are sometimes reported in combination with limb malformations, especially ring constrictions. This article describes three children with facial clefts and limb ring constrictions with various expressions. The first case has a lateral cleft with associated limb malformations. This combination has, to our knowledge, not yet been reported. The literature about facial clefting and the amniotic band syndrome and the possible etiology of clefting and constrictions in these cases are discussed
Original languageEnglish
Pages (from-to)661-667
JournalCleft palate-craniofacial journal
Issue number6
Publication statusPublished - 2010

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