TY - JOUR
T1 - Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)
AU - van Prooyen Schuurman, Lisanne
AU - van der Meij, KRM
AU - van Ravesteyn, Nicolien T.
AU - Kooij, Caroline
AU - Gitsels-van der Wal, JT
AU - Martin, L.
AU - Peters, I M
AU - Polak, M.
AU - van Vliet-Lachotzki, Elsbeth H.
AU - Galjaard, Robert-Jan H.
AU - Henneman, L
N1 - Funding Information: This study is supported by a grant from the Netherlands Organization for Health Research and Development (ZonMw) No. 543002001. Publisher Copyright: © 2022 The Authors. Prenatal Diagnosis published by John Wiley & Sons Ltd.
PY - 2022
Y1 - 2022
N2 - Objective: To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT). Method: A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3% of the respondents were of non-Western ethnic origin and 64.4% were religious. Results: Most respondents (77.2%) found the decision to decline NIPT easy to make, and 59.8% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were “I would never terminate my pregnancy” (57.1%) and “every child is welcome” (56.2%). For 16.9% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy. Conclusion: The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.
AB - Objective: To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT). Method: A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3% of the respondents were of non-Western ethnic origin and 64.4% were religious. Results: Most respondents (77.2%) found the decision to decline NIPT easy to make, and 59.8% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were “I would never terminate my pregnancy” (57.1%) and “every child is welcome” (56.2%). For 16.9% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy. Conclusion: The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.
KW - Non-invasive prenatal testing
KW - decision making
KW - prenatal genetic counseling
KW - prenatal screening
KW - religion
KW - socioeconomic status
UR - http://www.scopus.com/inward/record.url?scp=85138701625&partnerID=8YFLogxK
U2 - https://doi.org/10.1002/pd.6242
DO - https://doi.org/10.1002/pd.6242
M3 - Article
C2 - 36109868
SN - 0197-3851
JO - Prenatal diagnosis
JF - Prenatal diagnosis
ER -