TY - JOUR
T1 - Flavor perception and the risk of malnutrition in patients with Parkinson’s disease
AU - Roos, Dareia S.
AU - Oranje, Oscar J. M.
AU - Freriksen, Anneleen F. D.
AU - Berendse, Henk W.
AU - Boesveldt, Sanne
PY - 2018
Y1 - 2018
N2 - Flavor perception involves both olfactory and gustatory function. In patients with Parkinson’s disease (PD), hyposmia is a frequent finding, as well as an increased risk of malnutrition. We performed a pilot study to investigate the relationship between flavor perception and risk of malnutrition in PD patients. 63 PD patients participated to perform an olfactory (Sniffin’ Sticks) and gustatory (Taste Strips) task, and a questionnaire to establish nutritional risk (MUST), which includes BMI measurements. The relationship between olfactory and gustatory function and BMI was analyzed using partial correlations, corrected for disease duration, and regression analysis. Patients displayed a high prevalence of hyposmia (68.3%), and a low prevalence (6.3%) of hypogeusia. A small, but significant correlation was found between olfactory function and BMI (r = 0.261, p = 0.038), and not for gustatory function and BMI (r = 0.137, p = 0.284). Hyposmia, and not hypogeusia, may contribute to weight loss in Parkinson’s disease, and hence increase the risk of malnutrition.
AB - Flavor perception involves both olfactory and gustatory function. In patients with Parkinson’s disease (PD), hyposmia is a frequent finding, as well as an increased risk of malnutrition. We performed a pilot study to investigate the relationship between flavor perception and risk of malnutrition in PD patients. 63 PD patients participated to perform an olfactory (Sniffin’ Sticks) and gustatory (Taste Strips) task, and a questionnaire to establish nutritional risk (MUST), which includes BMI measurements. The relationship between olfactory and gustatory function and BMI was analyzed using partial correlations, corrected for disease duration, and regression analysis. Patients displayed a high prevalence of hyposmia (68.3%), and a low prevalence (6.3%) of hypogeusia. A small, but significant correlation was found between olfactory function and BMI (r = 0.261, p = 0.038), and not for gustatory function and BMI (r = 0.137, p = 0.284). Hyposmia, and not hypogeusia, may contribute to weight loss in Parkinson’s disease, and hence increase the risk of malnutrition.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85042382409&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/29470631
U2 - https://doi.org/10.1007/s00702-018-1862-8
DO - https://doi.org/10.1007/s00702-018-1862-8
M3 - Article
C2 - 29470631
SN - 0300-9564
VL - 125
SP - 925
EP - 930
JO - Journal of Neural Transmission
JF - Journal of Neural Transmission
IS - 6
ER -