TY - JOUR
T1 - Gender-specific prevalence of pilonidal sinus disease over time
T2 - A systematic review and meta-analysis
AU - Luedi, Markus M
AU - Schober, Patrick
AU - Stauffer, Verena K
AU - Diekmann, Maja
AU - Andereggen, Lukas
AU - Doll, Dietrich
N1 - Funding Information: The authors acknowledge Jeannie Wurz, Medical Editor from the Bern University Hospital, for careful reading and editing of the manuscript. Publisher Copyright: © 2021 The Authors. ANZ Journal of Surgery published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Surgeons. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/7/1
Y1 - 2021/7/1
N2 - Background: Gender-specific risk factors have been suggested to promote a fourfold higher incidence of pilonidal sinus disease (PSD) in male as compared to female patients. However, in recent decades there has been an apparent shift towards an increasing prevalence of PSD in women, as body weight and other risk factors influence the disease. We aimed at determining whether PSD prevalence actually changed in men and women over time. Methods: Following PRISMA guidelines (PROSPERO ID: 42016051588), databases were systematically searched. Papers reporting on PSD published between 1833 and 2018 in English, French, German, Italian and Spanish containing precise numbers of male and female participants were selected for analysis. Gender-specific prevalence of PSD over several decades was the main outcome measure. Results: We screened 679 studies reporting on 104 055 patients and found that the male/female ratio in patients with PSD has remained constant over time, with women being affected in about 20% of all PSD cases (I 2 = 96.18%; meta-regression p < 0.001). Conclusion: While the prevalence of PSD has risen over the past decades, the ratio between affected males and affected females has remained constant, with women invariably representing about 20% of patients despite wide ranging socioeconomic and behavioural changes.
AB - Background: Gender-specific risk factors have been suggested to promote a fourfold higher incidence of pilonidal sinus disease (PSD) in male as compared to female patients. However, in recent decades there has been an apparent shift towards an increasing prevalence of PSD in women, as body weight and other risk factors influence the disease. We aimed at determining whether PSD prevalence actually changed in men and women over time. Methods: Following PRISMA guidelines (PROSPERO ID: 42016051588), databases were systematically searched. Papers reporting on PSD published between 1833 and 2018 in English, French, German, Italian and Spanish containing precise numbers of male and female participants were selected for analysis. Gender-specific prevalence of PSD over several decades was the main outcome measure. Results: We screened 679 studies reporting on 104 055 patients and found that the male/female ratio in patients with PSD has remained constant over time, with women being affected in about 20% of all PSD cases (I 2 = 96.18%; meta-regression p < 0.001). Conclusion: While the prevalence of PSD has risen over the past decades, the ratio between affected males and affected females has remained constant, with women invariably representing about 20% of patients despite wide ranging socioeconomic and behavioural changes.
KW - gender medicine
KW - hair
KW - meta-analysis
KW - pilonidal sinus disease
UR - http://www.scopus.com/inward/record.url?scp=85107349280&partnerID=8YFLogxK
U2 - https://doi.org/10.1111/ans.16990
DO - https://doi.org/10.1111/ans.16990
M3 - Article
C2 - 34101331
SN - 1445-1433
VL - 91
SP - 1582
EP - 1587
JO - ANZ journal of surgery
JF - ANZ journal of surgery
IS - 7-8
ER -