@article{18f1a6dc523c4e539ec81d1f47b7c3b2,
title = "Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content",
abstract = "Bile acids (BAs) have been implicated in obesity-related conditions such as NAFLD and hyperlipidemia. Different human BAs exert variable biological activities. Chen et al. define genetic and microbial associations to plasma and fecal BA concentrations and composition in persons with obesity and establish their relationships with liver fat and lipid phenotypes.",
keywords = "bile acids, diabetes, enterohepatic circulation, fatty liver, genetics, gut microbiome, hyperlipidemia, liver, metabolic syndrome, obesity",
author = "Lianmin Chen and {van den Munckhof}, {Inge C. L.} and Kiki Schraa and {ter Horst}, Rob and Martijn Koehorst and {van Faassen}, Martijn and {van der Ley}, Claude and Marwah Doestzada and Zhernakova, {Daria V.} and Alexander Kurilshikov and Bloks, {Vincent W.} and Groen, {Albert K.} and Riksen, {Niels P.} and Rutten, {Joost H. W.} and Joosten, {Leo A. B.} and Cisca Wijmenga and Alexandra Zhernakova and {Human Functional Genomics Project} and Netea, {Mihai G.} and Jingyuan Fu and Folkert Kuipers",
year = "2020",
month = oct,
day = "6",
doi = "https://doi.org/10.1016/j.celrep.2020.108212",
language = "English",
volume = "33",
journal = "Cell reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "1",
}