Genetics

Rosa L. Schellevis, Camiel J. F. Boon, Anneke I. den Hollander, Eiko K. de Jong

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

This chapter focuses on the genetic causes of central serous chorioretinopathy (CSC). First, we summarize studies that support a genetic component in the etiology of CSC. Next, we provide a brief review of the genetic architecture of diseases and which techniques can be used to unravel these genetic components, followed by a summary of all candidate gene studies and a genome-wide association study that have been performed for CSC. The chapter concludes with a perspective about the implications of the robust association of the CFH gene with CSC, and future studies into the genetics of CSC are proposed.
Original languageEnglish
Title of host publicationCentral Serous Chorioretinopathy
PublisherElsevier
Pages49-70
ISBN (Electronic)9780128168004
DOIs
Publication statusPublished - 2019

Publication series

NameCentral Serous Chorioretinopathy

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