GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types

Philipp Sievers; Damian Stichel; Martin Sill; Daniel Schrimpf; Dominik Sturm; Florian Selt; Jonas Ecker; Daniel Kazdal; Evelina Miele; Mariëtte E. G. Kranendonk; Bastiaan B. J. Tops; Patricia Kohlhof-Meinecke; Rudi Beschorner; Christof M. Kramm; Martin Hasselblatt; Guido Reifenberger; David Capper; Pieter Wesseling; Albrecht Stenzinger; Till Milde; Andrey Korshunov; Olaf Witt; Stefan M. Pfister; Wolfgang Wick; Andreas von Deimling; David T. W. Jones; Felix Sahm

doi:https://doi.org/10.1007/s00401-021-02369-1

GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types

Philipp Sievers, Damian Stichel, Martin Sill, Daniel Schrimpf, Dominik Sturm, Florian Selt, Jonas Ecker, Daniel Kazdal, Evelina Miele, Mariëtte E. G. Kranendonk, Bastiaan B. J. Tops, Patricia Kohlhof-Meinecke, Rudi Beschorner, Christof M. Kramm, Martin Hasselblatt, Guido Reifenberger, David Capper, Pieter Wesseling, Albrecht Stenzinger, Till MildeAndrey Korshunov, Olaf Witt, Stefan M. Pfister, Wolfgang Wick, Andreas von Deimling, David T. W. Jones, Felix Sahm

Research output: Contribution to journal › Letter › Academic › peer-review

17 Citations (Scopus)

Original language	English
Pages (from-to)	1065-1069
Number of pages	5
Journal	Acta Neuropathologica
Volume	142
Issue number	6
Early online date	2021
DOIs	https://doi.org/10.1007/s00401-021-02369-1
Publication status	Published - Dec 2021

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Sievers, P., Stichel, D., Sill, M., Schrimpf, D., Sturm, D., Selt, F., Ecker, J., Kazdal, D., Miele, E., Kranendonk, M. E. G., Tops, B. B. J., Kohlhof-Meinecke, P., Beschorner, R., Kramm, C. M., Hasselblatt, M., Reifenberger, G., Capper, D., Wesseling, P., Stenzinger, A., ... Sahm, F. (2021). GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types. Acta Neuropathologica, 142(6), 1065-1069. https://doi.org/10.1007/s00401-021-02369-1

@article{1496d1439f2c45e68f2a84af8ec71a22,

title = "GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types",

author = "Philipp Sievers and Damian Stichel and Martin Sill and Daniel Schrimpf and Dominik Sturm and Florian Selt and Jonas Ecker and Daniel Kazdal and Evelina Miele and Kranendonk, {Mari{\"e}tte E. G.} and Tops, {Bastiaan B. J.} and Patricia Kohlhof-Meinecke and Rudi Beschorner and Kramm, {Christof M.} and Martin Hasselblatt and Guido Reifenberger and David Capper and Pieter Wesseling and Albrecht Stenzinger and Till Milde and Andrey Korshunov and Olaf Witt and Pfister, {Stefan M.} and Wolfgang Wick and {von Deimling}, Andreas and Jones, {David T. W.} and Felix Sahm",

note = "Funding Information: We thank J. Meyer, L. Hofmann and A. Habel for skillful technical assistance and the microarray unit of the DKFZ Genomics and Proteomics Core Facility for providing Illumina DNA methylation array-related services. This study was supported by the Hertie Network of Excellence in Clinical Neuroscience. P.S. is a fellow of the Hertie Academy of Excellence in Clinical Neuroscience. D.T.W.J. is supported by the Everest Centre for Low-Grade Paediatric Brain Tumours (the Brain Tumour Charity, UK; GN-000382). Funding Information: We thank J. Meyer, L. Hofmann and A. Habel for skillful technical assistance and the microarray unit of the DKFZ Genomics and Proteomics Core Facility for providing Illumina DNA methylation array-related services. This study was supported by the Hertie Network of Excellence in Clinical Neuroscience. P.S. is a fellow of the Hertie Academy of Excellence in Clinical Neuroscience. D.T.W.J. is supported by the Everest Centre for Low-Grade Paediatric Brain Tumours (the Brain Tumour Charity, UK; GN-000382).",

year = "2021",

month = dec,

doi = "https://doi.org/10.1007/s00401-021-02369-1",

language = "English",

volume = "142",

pages = "1065--1069",

journal = "Acta Neuropathologica",

issn = "0001-6322",

publisher = "Springer Verlag",

number = "6",

}

Sievers, P, Stichel, D, Sill, M, Schrimpf, D, Sturm, D, Selt, F, Ecker, J, Kazdal, D, Miele, E, Kranendonk, MEG, Tops, BBJ, Kohlhof-Meinecke, P, Beschorner, R, Kramm, CM, Hasselblatt, M, Reifenberger, G, Capper, D, Wesseling, P, Stenzinger, A, Milde, T, Korshunov, A, Witt, O, Pfister, SM, Wick, W, von Deimling, A, Jones, DTW & Sahm, F 2021, 'GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types', Acta Neuropathologica, vol. 142, no. 6, pp. 1065-1069. https://doi.org/10.1007/s00401-021-02369-1

TY - JOUR

T1 - GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types

AU - Sievers, Philipp

AU - Stichel, Damian

AU - Sill, Martin

AU - Schrimpf, Daniel

AU - Sturm, Dominik

AU - Selt, Florian

AU - Ecker, Jonas

AU - Kazdal, Daniel

AU - Miele, Evelina

AU - Kranendonk, Mariëtte E. G.

AU - Tops, Bastiaan B. J.

AU - Kohlhof-Meinecke, Patricia

AU - Beschorner, Rudi

AU - Kramm, Christof M.

AU - Hasselblatt, Martin

AU - Reifenberger, Guido

AU - Capper, David

AU - Wesseling, Pieter

AU - Stenzinger, Albrecht

AU - Milde, Till

AU - Korshunov, Andrey

AU - Witt, Olaf

AU - Pfister, Stefan M.

AU - Wick, Wolfgang

AU - von Deimling, Andreas

AU - Jones, David T. W.

AU - Sahm, Felix

N1 - Funding Information: We thank J. Meyer, L. Hofmann and A. Habel for skillful technical assistance and the microarray unit of the DKFZ Genomics and Proteomics Core Facility for providing Illumina DNA methylation array-related services. This study was supported by the Hertie Network of Excellence in Clinical Neuroscience. P.S. is a fellow of the Hertie Academy of Excellence in Clinical Neuroscience. D.T.W.J. is supported by the Everest Centre for Low-Grade Paediatric Brain Tumours (the Brain Tumour Charity, UK; GN-000382). Funding Information: We thank J. Meyer, L. Hofmann and A. Habel for skillful technical assistance and the microarray unit of the DKFZ Genomics and Proteomics Core Facility for providing Illumina DNA methylation array-related services. This study was supported by the Hertie Network of Excellence in Clinical Neuroscience. P.S. is a fellow of the Hertie Academy of Excellence in Clinical Neuroscience. D.T.W.J. is supported by the Everest Centre for Low-Grade Paediatric Brain Tumours (the Brain Tumour Charity, UK; GN-000382).

PY - 2021/12

Y1 - 2021/12

UR - http://www.scopus.com/inward/record.url?scp=85115177261&partnerID=8YFLogxK

U2 - https://doi.org/10.1007/s00401-021-02369-1

DO - https://doi.org/10.1007/s00401-021-02369-1

M3 - Letter

C2 - 34536122

SN - 0001-6322

VL - 142

SP - 1065

EP - 1069

JO - Acta Neuropathologica

JF - Acta Neuropathologica

IS - 6

ER -

GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types

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