TY - JOUR
T1 - HIV, leukemia, and new horizons in molecular therapy
AU - Berkhout, Ben
PY - 2013
Y1 - 2013
N2 - Cancer and human immunodeficiency virus (HIV) are both scary things to have in your body, but a new treatment is successfully using the latter against the former. Recent news reports, among others in the New York Times, talked about this new cure for leukemia by using HIV. This mini-review puts this news in perspective and provides a broader view as there appear to be several areas where clinical research on HIV and leukemia seem to connect. The topics covered range from antiviral gene therapy approaches using HIV-based lentiviral vectors to the risk of leukemia induction by these integrating vectors, and from an anti-leukemia transplantation strategy that turned out to provide a functional cure for HIV, to novel vaccination approaches
AB - Cancer and human immunodeficiency virus (HIV) are both scary things to have in your body, but a new treatment is successfully using the latter against the former. Recent news reports, among others in the New York Times, talked about this new cure for leukemia by using HIV. This mini-review puts this news in perspective and provides a broader view as there appear to be several areas where clinical research on HIV and leukemia seem to connect. The topics covered range from antiviral gene therapy approaches using HIV-based lentiviral vectors to the risk of leukemia induction by these integrating vectors, and from an anti-leukemia transplantation strategy that turned out to provide a functional cure for HIV, to novel vaccination approaches
U2 - https://doi.org/10.1016/j.jfma.2013.01.009
DO - https://doi.org/10.1016/j.jfma.2013.01.009
M3 - Review article
C2 - 24016608
SN - 0929-6646
VL - 112
SP - 441
EP - 444
JO - Journal of the Formosan Medical Association = Taiwan yi zhi
JF - Journal of the Formosan Medical Association = Taiwan yi zhi
IS - 8
ER -