Hormones in the critically ill patient: To intervene or not to intervene?

J. Ligtenberg; A. Girbes; J. Beentjes; J. Tulleken; T. Werf; J. Zijlstra

doi:https://doi.org/10.1007/s001340101050

Hormones in the critically ill patient: To intervene or not to intervene?

J. Ligtenberg, A. Girbes, J. Beentjes, J. Tulleken, T. Werf, J. Zijlstra

Research output: Contribution to journal › Review article › Academic › peer-review

33 Citations (Scopus)

Abstract

Critically ill patients show a variety of hormonal changes that appear to differ considerably in acute and prolonged critical illness. Whether these endocrine alterations serve as physiological adaptation or contribute to further deterioration remains an intriguing question. We review the recent literature and discuss whether measuring circulating hormone concentrations, performing stimulation tests, and intervening with hormone substitution could contribute to the recovery of critically ill patients.

Original language	English
Pages (from-to)	1567-1577
Number of pages	11
Journal	Intensive care medicine
Volume	27
Issue number	10
DOIs	https://doi.org/10.1007/s001340101050
Publication status	Published - 13 Nov 2001

Keywords

Cortisol
Critical illness
Growth hormone
Insulin resistance
Intensive care
Norepinephrine
Prolactin
Relative adrenal insufficiency syndrome
Synacthen
Thyroid hormones

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https://doi.org/10.1007/s001340101050

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abstract = "Critically ill patients show a variety of hormonal changes that appear to differ considerably in acute and prolonged critical illness. Whether these endocrine alterations serve as physiological adaptation or contribute to further deterioration remains an intriguing question. We review the recent literature and discuss whether measuring circulating hormone concentrations, performing stimulation tests, and intervening with hormone substitution could contribute to the recovery of critically ill patients.",

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AU - Werf, T.

AU - Zijlstra, J.

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AB - Critically ill patients show a variety of hormonal changes that appear to differ considerably in acute and prolonged critical illness. Whether these endocrine alterations serve as physiological adaptation or contribute to further deterioration remains an intriguing question. We review the recent literature and discuss whether measuring circulating hormone concentrations, performing stimulation tests, and intervening with hormone substitution could contribute to the recovery of critically ill patients.

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KW - Critical illness

KW - Growth hormone

KW - Insulin resistance

KW - Intensive care

KW - Norepinephrine

KW - Prolactin

KW - Relative adrenal insufficiency syndrome

KW - Synacthen

KW - Thyroid hormones

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JO - Intensive care medicine

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Hormones in the critically ill patient: To intervene or not to intervene?

Abstract

Keywords

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