TY - JOUR
T1 - How are you doing in the eyes of your spouse? Level of agreement between the self-completed EQ-5D-5L and two proxy perspectives in an orthopaedic population: a randomized agreement study
AU - Tol, Maria C. J. M.
AU - Kuipers, Jurrian P.
AU - Willigenburg, Nienke W.
AU - Willems, Hanna C.
AU - Poolman, Rudolf W.
N1 - Funding Information: This study was by the Netherlands Organization for Health Research and Development (ZonMw) (Grant Number 843004112). Publisher Copyright: © 2021, The Author(s).
PY - 2021/12/1
Y1 - 2021/12/1
N2 - Objectives: To determine the level of agreement between both proxy versions and the self-completed EQ-5D-5L. Design: A randomized agreement study. Setting and participants: We recruited 120 patients (compos mentis) and their proxies at the orthopaedic outpatient clinic. Patients completed the regular EQ-5D-5L and their proxy completed the proxy version of the EQ-5D-5L and rated the patients’ health from their own (proxy-proxy) perspective (i.e. how do you rate the health of the patient), and from the patient’s (proxy-patient) perspective (i.e. how do you think the patient would rate their own health if they were able to). Measures: The primary outcome was the agreement between patients and their proxy, quantified as the intra class correlation coefficient for the EQ-5D-5L Utility score. Results: Average Utility scores were 0.65 with the self completed EQ-5D-5L, versus 0.60 with the proxy-patient version and 0.58 with the proxy-proxy version. The ICC was 0.66 (95% CI 0.523, 0.753) for the proxy-patient perspective and 0.58 (95% CI 0.411, 0.697) for the proxy-proxy perspective. The mean gold standard score of the VAS-Health was 69.7 whereas the proxy-proxy perspective was 66.5 and the proxy-patient perspective was 66.3. Conclusion and implications: The proxy-patient perspective yielded substantial agreement with the self completed EQ-5D-5L, while the agreement with the proxy-proxy perspective was moderate. In this study population of patients without cognitive impairment, proxies tended to underestimate the quality of life of their relative.
AB - Objectives: To determine the level of agreement between both proxy versions and the self-completed EQ-5D-5L. Design: A randomized agreement study. Setting and participants: We recruited 120 patients (compos mentis) and their proxies at the orthopaedic outpatient clinic. Patients completed the regular EQ-5D-5L and their proxy completed the proxy version of the EQ-5D-5L and rated the patients’ health from their own (proxy-proxy) perspective (i.e. how do you rate the health of the patient), and from the patient’s (proxy-patient) perspective (i.e. how do you think the patient would rate their own health if they were able to). Measures: The primary outcome was the agreement between patients and their proxy, quantified as the intra class correlation coefficient for the EQ-5D-5L Utility score. Results: Average Utility scores were 0.65 with the self completed EQ-5D-5L, versus 0.60 with the proxy-patient version and 0.58 with the proxy-proxy version. The ICC was 0.66 (95% CI 0.523, 0.753) for the proxy-patient perspective and 0.58 (95% CI 0.411, 0.697) for the proxy-proxy perspective. The mean gold standard score of the VAS-Health was 69.7 whereas the proxy-proxy perspective was 66.5 and the proxy-patient perspective was 66.3. Conclusion and implications: The proxy-patient perspective yielded substantial agreement with the self completed EQ-5D-5L, while the agreement with the proxy-proxy perspective was moderate. In this study population of patients without cognitive impairment, proxies tended to underestimate the quality of life of their relative.
UR - http://www.scopus.com/inward/record.url?scp=85099805025&partnerID=8YFLogxK
U2 - https://doi.org/10.1186/s12955-021-01679-y
DO - https://doi.org/10.1186/s12955-021-01679-y
M3 - Article
C2 - 33499876
SN - 1477-7525
VL - 19
JO - Health and quality of life outcomes
JF - Health and quality of life outcomes
IS - 1
M1 - 35
ER -