Impact of site-specific phosphorylation of protein kinase A sites Ser(23) and Ser(24) of cardiac troponin I in human cardiomyocytes

P.J.M. Wijnker; D.B. Foster; A.L. Tsao; A.H. Frazier; C.G. dos Remedios; A.M. Murphy; G.J.M. Stienen; J. van der Velden

doi:https://doi.org/10.1152/ajpheart.00498.2012

Impact of site-specific phosphorylation of protein kinase A sites Ser(23) and Ser(24) of cardiac troponin I in human cardiomyocytes

P.J.M. Wijnker, D.B. Foster, A.L. Tsao, A.H. Frazier, C.G. dos Remedios, A.M. Murphy, G.J.M. Stienen, J. van der Velden

Physiology (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

46 Citations (Scopus)

Abstract

PKA-mediated phosphorylation of contractile proteins upon β-adrenergic stimulation plays an important role in the regulation of cardiac performance. Phosphorylation of the PKA sites (Ser

Original language	English
Pages (from-to)	H260-H268
Journal	American journal of physiology. Heart and circulatory physiology
Volume	304
Issue number	2
DOIs	https://doi.org/10.1152/ajpheart.00498.2012
Publication status	Published - 2013

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Cite this

Wijnker, P. J. M., Foster, D. B., Tsao, A. L., Frazier, A. H., dos Remedios, C. G., Murphy, A. M., Stienen, G. J. M., & van der Velden, J. (2013). Impact of site-specific phosphorylation of protein kinase A sites Ser(23) and Ser(24) of cardiac troponin I in human cardiomyocytes. American journal of physiology. Heart and circulatory physiology, 304(2), H260-H268. https://doi.org/10.1152/ajpheart.00498.2012

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abstract = "PKA-mediated phosphorylation of contractile proteins upon β-adrenergic stimulation plays an important role in the regulation of cardiac performance. Phosphorylation of the PKA sites (Ser",

author = "P.J.M. Wijnker and D.B. Foster and A.L. Tsao and A.H. Frazier and {dos Remedios}, C.G. and A.M. Murphy and G.J.M. Stienen and {van der Velden}, J.",

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Wijnker, PJM, Foster, DB, Tsao, AL, Frazier, AH, dos Remedios, CG, Murphy, AM, Stienen, GJM & van der Velden, J 2013, 'Impact of site-specific phosphorylation of protein kinase A sites Ser(23) and Ser(24) of cardiac troponin I in human cardiomyocytes', American journal of physiology. Heart and circulatory physiology, vol. 304, no. 2, pp. H260-H268. https://doi.org/10.1152/ajpheart.00498.2012

Impact of site-specific phosphorylation of protein kinase A sites Ser(23) and Ser(24) of cardiac troponin I in human cardiomyocytes. / Wijnker, P.J.M.; Foster, D.B.; Tsao, A.L. et al.
In: American journal of physiology. Heart and circulatory physiology, Vol. 304, No. 2, 2013, p. H260-H268.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Frazier, A.H.

AU - dos Remedios, C.G.

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