TY - JOUR
T1 - Improving Care in Eosinophil-Associated Diseases
T2 - A Charter
AU - Jackson, David J.
AU - Akuthota, Praveen
AU - Andradas, Rebeca
AU - Bredenoord, Albert J.
AU - Cordell, Amanda
AU - Gray, Sarah
AU - Kullman, Joyce
AU - Mathur, Sameer K.
AU - Pavord, Ian
AU - Roufosse, Florence
AU - Rubio, Christian
AU - Rusek, Irena Clisson
AU - Simon, Dagmar
AU - Strobel, Mary Jo
AU - Winders, Tonya
N1 - Funding Information: David J. Jackson has received consulting and speaker fees and support to attend international congresses from AstraZeneca, GSK, Sanofi, Teva, BI, Novartis, Chiesi, and Napp. Praveen Akuthota has received consulting fees and research support from AstraZeneca and GlaxoSmithKline; research support from Regeneron; consulting fees from Advance Medical; grant support from the National Institutes of Health (USA) and the American Partnership for Eosinophilic Disorders; royalties from UpToDate; and honoraria from Medscape/WebMD, AKH, Prime CME, Rockpointe, and Vindico. Albert J. Bredenoord received research funding from Nutricia, Norgine, Thelial, SST, and Bayer and received speaker and/or consulting fees from Laborie, Arena, EsoCap, Medtronic, Dr. Falk Pharma, Calypso Biotech, Alimentiv, Sanofi, Reckett, Regeneron, and AstraZeneca. Amanda Cordell has received consulting and speaker fees from AstraZeneca, Avir, Regeneron/Sanofi, and Dr. Falk Pharma. Sarah Gray has received consulting fees from AstraZeneca. Sameer Mathur received consulting and speaker fees from AstraZeneca, GSK, Regeneron, and ALK Abello and research funding from Novartis. Florence Roufosse has received consulting fees from AstraZeneca and GlaxoSmithKline for drug development in hypereosinophilic syndromes and royalties from UpToDate. Tonya Winders has received consulting and speaker fees from AstraZeneca, GSK, Sanofi, Regeneron, ALK Abello, and Novartis. Publisher Copyright: © 2022, The Author(s).
PY - 2022/6
Y1 - 2022/6
N2 - Eosinophil-associated diseases (EADs) are a range of heterogeneous conditions in which eosinophils are believed to play a critical pathological role. EADs include common illnesses such as eosinophilic asthma and chronic rhinosinusitis and rare conditions such as hypereosinophilic syndromes (HES) and eosinophilic gastrointestinal disorders (EGIDs). EADs are associated with substantial burdens for the patient, including chronic, debilitating symptoms, increased financial burden, decreased health-related quality of life, and the need for repeated visits to multiple different healthcare professionals (HCPs), emergency departments, and/or hospitals. Poor EAD recognition by HCPs often contributes to delayed diagnoses, which further delays patient access to appropriate care and effective treatments, contributing to poor health outcomes. The objective of this charter is to outline key patient rights and expectations with respect to the management of their condition(s) and to set forth an ambitious action plan to improve health outcomes for patients with EADs: (1) people with EADs, their caretakers, HCPs, and the public must have greater awareness and education about EADs; (2) people with EADs must receive a timely, accurate diagnosis; (3) all people with EADs must have access to an appropriate multidisciplinary team, when necessary; and (4) people with EADs must have access to safe and effective treatment options without unnecessary regulatory delays. The principles described in this charter demonstrate the core elements of quality care that people with EADs must receive, and they represent clear steps by which to reduce patient and caregiver burden and improve patient outcomes. We urge HCPs, healthcare systems, and policymakers worldwide to swiftly adopt these principles to ensure patients with EADs have an accurate diagnosis in a timely manner and access to high-level care and treatment in an appropriate setting.
AB - Eosinophil-associated diseases (EADs) are a range of heterogeneous conditions in which eosinophils are believed to play a critical pathological role. EADs include common illnesses such as eosinophilic asthma and chronic rhinosinusitis and rare conditions such as hypereosinophilic syndromes (HES) and eosinophilic gastrointestinal disorders (EGIDs). EADs are associated with substantial burdens for the patient, including chronic, debilitating symptoms, increased financial burden, decreased health-related quality of life, and the need for repeated visits to multiple different healthcare professionals (HCPs), emergency departments, and/or hospitals. Poor EAD recognition by HCPs often contributes to delayed diagnoses, which further delays patient access to appropriate care and effective treatments, contributing to poor health outcomes. The objective of this charter is to outline key patient rights and expectations with respect to the management of their condition(s) and to set forth an ambitious action plan to improve health outcomes for patients with EADs: (1) people with EADs, their caretakers, HCPs, and the public must have greater awareness and education about EADs; (2) people with EADs must receive a timely, accurate diagnosis; (3) all people with EADs must have access to an appropriate multidisciplinary team, when necessary; and (4) people with EADs must have access to safe and effective treatment options without unnecessary regulatory delays. The principles described in this charter demonstrate the core elements of quality care that people with EADs must receive, and they represent clear steps by which to reduce patient and caregiver burden and improve patient outcomes. We urge HCPs, healthcare systems, and policymakers worldwide to swiftly adopt these principles to ensure patients with EADs have an accurate diagnosis in a timely manner and access to high-level care and treatment in an appropriate setting.
KW - Eosinophil-associated diseases
KW - Eosinophilic immune dysfunction (EID)
KW - Healthcare professional (HCP) education
KW - Multidisciplinary teams (MDTs)
KW - Patient education
KW - Patient rights
KW - Timely diagnosis
UR - http://www.scopus.com/inward/record.url?scp=85129197497&partnerID=8YFLogxK
U2 - https://doi.org/10.1007/s12325-022-02110-8
DO - https://doi.org/10.1007/s12325-022-02110-8
M3 - Comment/Letter to the editor
C2 - 35489014
SN - 0741-238X
VL - 39
SP - 2323
EP - 2341
JO - Advances in therapy
JF - Advances in therapy
IS - 6
ER -