Improving embryo quality in assisted reproduction

E. Mantikou

Research output: PhD ThesisPhD-Thesis - Research and graduation internal


The goal of this thesis was to improve embryo quality in assisted reproductive technologies by gaining more insight into human preimplantation embryo development and by improving in vitro culture conditions. To do so, we investigated an intriguing feature of the human preimplantation embryo, i.e. its mosaic nature, and the occurrence of mitotic aneuploidies. To improve in vitro culture conditions, we aimed to elucidate the effect of culture media on human preimplantation embryo development, and on the success rates of IVF/ICSI treatment.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Repping, S., Supervisor
  • Mastenbroek, Sebastiaan, Co-supervisor
Award date3 Dec 2013
Publication statusPublished - 2013

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