Induction of cell-associated chemokines after endotoxin administration to healthy humans

D. P. Olszyna, E. de Jonge, P. E. Dekkers, S. J. van Deventer, T. van der Poll

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Abstract

Erythrocytes express the Duffy antigen receptor for chemokines. Endotoxin injection into humans induced high levels of interleukin-8 (IL-8), growth-related oncogene alpha, and monocyte chemoattractant protein 1 in circulating erythrocytes. IL-8 was also recovered from mononuclear and polymorphonuclear cells. Cell-associated chemokines may more accurately reflect their production than plasma concentrations
Original languageEnglish
Pages (from-to)2736-2738
JournalInfection and immunity
Volume69
Issue number4
DOIs
Publication statusPublished - 2001

Cite this