Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.

J. Sigmond; HH Backus; D. Wouters; O.H. Temmink; G. Jansen; G.J. Peters

doi:https://doi.org/10.1016/S0006-2952(03)00287-9

Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.

J. Sigmond, HH Backus, D. Wouters, O.H. Temmink, G. Jansen, G.J. Peters

VU University medical center

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	431-8
Journal	Biochemical Pharmacology
Volume	66
Issue number	3
DOIs	https://doi.org/10.1016/S0006-2952(03)00287-9
Publication status	Published - 2003

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https://doi.org/10.1016/S0006-2952(03)00287-9

Cite this

@article{79088a9f8af549ea8c4b90b519284637,

title = "Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.",

author = "J. Sigmond and HH Backus and D. Wouters and O.H. Temmink and G. Jansen and G.J. Peters",

year = "2003",

doi = "https://doi.org/10.1016/S0006-2952(03)00287-9",

language = "English",

volume = "66",

pages = "431--8",

journal = "Biochemical pharmacology",

issn = "0006-2952",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression.

AU - Sigmond, J.

AU - Backus, HH

AU - Wouters, D.

AU - Temmink, O.H.

AU - Jansen, G.

AU - Peters, G.J.

PY - 2003

Y1 - 2003

U2 - https://doi.org/10.1016/S0006-2952(03)00287-9

DO - https://doi.org/10.1016/S0006-2952(03)00287-9

M3 - Article

SN - 0006-2952

VL - 66

SP - 431

EP - 438

JO - Biochemical pharmacology

JF - Biochemical pharmacology

IS - 3

ER -