Inflammatory biomarkers do not differ between persistently seronegative vs seropositive people with HIV after treatment in early acute HIV infection

Catherine W. Cai, Suteeraporn Pinyakorn, Eugène Kroon, Mark de Souza, Donn J. Colby, Tippawan Pankam, Supanit Pattanachaiwit, Sasiwimol Ubolyam, Adam Rupert, Perrine Lallemand, Robin Dewar, Helene C. Highbarger, Jintanat Ananworanich, Sandhya Vasan, Irini Sereti

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2 Citations (Scopus)

Abstract

Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and interleukin-6, indicating that seronegativity does not affect chronic inflammation in early treated PWH.
Original languageEnglish
Article numberofaa383
JournalOpen forum infectious diseases
Volume7
Issue number9
DOIs
Publication statusPublished - 1 Sep 2020

Keywords

  • AIDS
  • Chronic inflammation
  • Coagulopathy
  • HIV
  • Viral reservoir

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