TY - JOUR
T1 - Influence of neonatal endotracheal tube dimensions on oscillometry-acquired reactance
T2 - a bench study
AU - Pigmans, Rosemijne R. W. P.
AU - van Leuteren, Ruud W.
AU - Scholten, Anouk W. J.
AU - Veneroni, Chiara
AU - van Kaam, Anton H.
AU - Hutten, Jeroen
AU - Dellacà, Raffaele L.
AU - de Jongh, Frans H. C.
N1 - Funding Information: RP, RvL, AS, JH and FJ conceptualized the study. RP performed the measurements, analysed the data and wrote the first version of the manuscript. All authors contributed to the interpretation of the study results and critically reviewed and contributed to the final draft of the manuscript. Publisher Copyright: © 2023 The Author(s). Published on behalf of Institute of Physics and Engineering in Medicine by IOP Publishing Ltd.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Objective. To examine the influence of the endotracheal tube (ETT) on respiratory reactance (Xrs) measured with the forced oscillation technique (FOT) and develop a correction method for it. Approach. In a bench study, the reactance of ETTs (Xtube) with different dimensions was measured on a breathing test lung in various respiratory settings. Main results. Xtube can be accurately predicted by a fitted formula, with an R2 of 0.97, with negligible effects due to changes in respiratory pattern and lung volume. Significance. The developed formula offers the ability to measure ETT-independent Xrs values of patients, improving the potential of FOT for lung function testing in mechanically ventilated newborns.
AB - Objective. To examine the influence of the endotracheal tube (ETT) on respiratory reactance (Xrs) measured with the forced oscillation technique (FOT) and develop a correction method for it. Approach. In a bench study, the reactance of ETTs (Xtube) with different dimensions was measured on a breathing test lung in various respiratory settings. Main results. Xtube can be accurately predicted by a fitted formula, with an R2 of 0.97, with negligible effects due to changes in respiratory pattern and lung volume. Significance. The developed formula offers the ability to measure ETT-independent Xrs values of patients, improving the potential of FOT for lung function testing in mechanically ventilated newborns.
KW - infants
KW - mechanical ventilation
KW - oscillometry
KW - respiratory mechanics
UR - http://www.scopus.com/inward/record.url?scp=85147143399&partnerID=8YFLogxK
U2 - https://doi.org/10.1088/1361-6579/acb03a
DO - https://doi.org/10.1088/1361-6579/acb03a
M3 - Article
C2 - 36599175
SN - 0967-3334
VL - 44
JO - Physiological measurement
JF - Physiological measurement
IS - 1
M1 - 01NT01
ER -