Influence of neonatal endotracheal tube dimensions on oscillometry-acquired reactance: a bench study

Rosemijne R. W. P. Pigmans, Ruud W. van Leuteren, Chiara Veneroni, Anton H. van Kaam, Jeroen Hutten, Raffaele L. Dellacà, Frans H. C. de Jongh, Anouk W. J. Scholten

Research output: Contribution to journalArticleAcademicpeer-review


Objective. To examine the influence of the endotracheal tube (ETT) on respiratory reactance (Xrs) measured with the forced oscillation technique (FOT) and develop a correction method for it. Approach. In a bench study, the reactance of ETTs (Xtube) with different dimensions was measured on a breathing test lung in various respiratory settings. Main results. Xtube can be accurately predicted by a fitted formula, with an R2 of 0.97, with negligible effects due to changes in respiratory pattern and lung volume. Significance. The developed formula offers the ability to measure ETT-independent Xrs values of patients, improving the potential of FOT for lung function testing in mechanically ventilated newborns.
Original languageEnglish
Article number01NT01
JournalPhysiological measurement
Issue number1
Publication statusPublished - 1 Jan 2023


  • infants
  • mechanical ventilation
  • oscillometry
  • respiratory mechanics

Cite this