Insulin-dependent signaling: regulation by amino acids and energy

A. J. Meijer

doi:https://doi.org/10.1080/15376520490257419

Insulin-dependent signaling: regulation by amino acids and energy

A. J. Meijer

Medical Biochemistry (AMC)

Research output: Contribution to journal › Article* › Academic › peer-review

Abstract

Recent research has indicated that amino acids stimulate a signal-transduction pathway that is also used by insulin. Moreover, for insulin to exert its anabolic and anticatabolic effects on protein, there is an absolute requirement for amino acids. This signaling pathway becomes inhibited by adenosine monophosphate-activated protein kinase when energy production falls short. In this brief review some of the experimental evidence is discussed

Original language	English
Pages (from-to)	31-34
Journal	Toxicology mechanisms and methods
Volume	14
Issue number	1-2
DOIs	https://doi.org/10.1080/15376520490257419
Publication status	Published - 2004

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https://doi.org/10.1080/15376520490257419

Cite this

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title = "Insulin-dependent signaling: regulation by amino acids and energy",

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AB - Recent research has indicated that amino acids stimulate a signal-transduction pathway that is also used by insulin. Moreover, for insulin to exert its anabolic and anticatabolic effects on protein, there is an absolute requirement for amino acids. This signaling pathway becomes inhibited by adenosine monophosphate-activated protein kinase when energy production falls short. In this brief review some of the experimental evidence is discussed

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