Insulin-dependent signaling: regulation by amino acids and energy

A. J. Meijer

Research output: Contribution to journalArticle*Academicpeer-review


Recent research has indicated that amino acids stimulate a signal-transduction pathway that is also used by insulin. Moreover, for insulin to exert its anabolic and anticatabolic effects on protein, there is an absolute requirement for amino acids. This signaling pathway becomes inhibited by adenosine monophosphate-activated protein kinase when energy production falls short. In this brief review some of the experimental evidence is discussed
Original languageEnglish
Pages (from-to)31-34
JournalToxicology mechanisms and methods
Issue number1-2
Publication statusPublished - 2004

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