Interpreting Results in Clinical Research: Overview of Measures of Effect, Measures of Precision, and Measures of Diagnostic Accuracy for Clinicians and Researchers

Marcello Di Nisio, Harry R. Büller, Patrick M.M. Bossuyt, Holger J. Schünemann

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Original languageEnglish
Title of host publicationEvidence-Based Hematology
PublisherJohn Wiley and Sons Inc.
Pages15-22
Number of pages8
ISBN (Print)9781405157476
DOIs
Publication statusPublished - 4 Feb 2009

Keywords

  • Diagnostic accuracy measures
  • Interpreting results in clinical research
  • Likelihood ratios contrasting proportions of patients with and without target disorder
  • Measures of precision
  • Number needed to treat (NNT) or the number needed to harm (NNH)
  • Sensitivity, specificity, and predictive values of diagnostic tests
  • Test accuracy - surrogate for patient outcomes
  • Test and treatment thresholds

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