Investigating the efficacy of integrated cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial

Katelijne van Emmerik-van Oortmerssen; Ellen Vedel; Maarten W. Koeter; Kim de Bruijn; Jack J. M. Dekker; Wim van den Brink; Robert A. Schoevers; K. van Emmerink-van Oortmerssen

doi:https://doi.org/10.1186/1471-244X-13-132

Investigating the efficacy of integrated cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial

Katelijne van Emmerik-van Oortmerssen, Ellen Vedel, Maarten W. Koeter, Kim de Bruijn, Jack J. M. Dekker, Wim van den Brink, Robert A. Schoevers, K. van Emmerink-van Oortmerssen

Research output: Contribution to journal › Article › Academic › peer-review

25 Citations (Scopus)

Abstract

Attention deficit hyperactivity disorder (ADHD) frequently co-occurs with substance use disorders (SUD). The combination of ADHD and SUD is associated with a negative prognosis of both SUD and ADHD. Pharmacological treatments of comorbid ADHD in adult patients with SUD have not been very successful. Recent studies show positive effects of cognitive behavioral therapy (CBT) in ADHD patients without SUD, but CBT has not been studied in ADHD patients with comorbid SUD. This paper presents the protocol of a randomized controlled trial to test the efficacy of an integrated CBT protocol aimed at reducing SUD as well as ADHD symptoms in SUD patients with a comorbid diagnosis of ADHD. The experimental group receives 15 CBT sessions directed at symptom reduction of SUD as well as ADHD. The control group receives treatment as usual, i.e. 10 CBT sessions directed at symptom reduction of SUD only. The primary outcome is the level of self-reported ADHD symptoms. Secondary outcomes include measures of substance use, depression and anxiety, quality of life, health care consumption and neuropsychological functions. This is the first randomized controlled trial to test the efficacy of an integrated CBT protocol for adult SUD patients with a comorbid diagnosis of ADHD. The rationale for the trial, the design, and the strengths and limitations of the study are discussed

Original language	English
Article number	132
Pages (from-to)	132
Journal	BMC psychiatry
Volume	13
Issue number	1
DOIs	https://doi.org/10.1186/1471-244X-13-132
Publication status	Published - 2013

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https://doi.org/10.1186/1471-244X-13-132

Cite this

van Emmerik-van Oortmerssen, K., Vedel, E., Koeter, M. W., de Bruijn, K., Dekker, J. J. M., van den Brink, W., Schoevers, R. A., & van Emmerink-van Oortmerssen, K. (2013). Investigating the efficacy of integrated cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial. BMC psychiatry, 13(1), 132. Article 132. https://doi.org/10.1186/1471-244X-13-132

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abstract = "Attention deficit hyperactivity disorder (ADHD) frequently co-occurs with substance use disorders (SUD). The combination of ADHD and SUD is associated with a negative prognosis of both SUD and ADHD. Pharmacological treatments of comorbid ADHD in adult patients with SUD have not been very successful. Recent studies show positive effects of cognitive behavioral therapy (CBT) in ADHD patients without SUD, but CBT has not been studied in ADHD patients with comorbid SUD. This paper presents the protocol of a randomized controlled trial to test the efficacy of an integrated CBT protocol aimed at reducing SUD as well as ADHD symptoms in SUD patients with a comorbid diagnosis of ADHD. The experimental group receives 15 CBT sessions directed at symptom reduction of SUD as well as ADHD. The control group receives treatment as usual, i.e. 10 CBT sessions directed at symptom reduction of SUD only. The primary outcome is the level of self-reported ADHD symptoms. Secondary outcomes include measures of substance use, depression and anxiety, quality of life, health care consumption and neuropsychological functions. This is the first randomized controlled trial to test the efficacy of an integrated CBT protocol for adult SUD patients with a comorbid diagnosis of ADHD. The rationale for the trial, the design, and the strengths and limitations of the study are discussed",

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year = "2013",

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van Emmerik-van Oortmerssen, K, Vedel, E, Koeter, MW, de Bruijn, K, Dekker, JJM, van den Brink, W, Schoevers, RA & van Emmerink-van Oortmerssen, K 2013, 'Investigating the efficacy of integrated cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial', BMC psychiatry, vol. 13, no. 1, 132, pp. 132. https://doi.org/10.1186/1471-244X-13-132

Investigating the efficacy of integrated cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial. / van Emmerik-van Oortmerssen, Katelijne; Vedel, Ellen; Koeter, Maarten W. et al.
In: BMC psychiatry, Vol. 13, No. 1, 132, 2013, p. 132.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - de Bruijn, Kim

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van Emmerik-van Oortmerssen K, Vedel E, Koeter MW, de Bruijn K, Dekker JJM, van den Brink W et al. Investigating the efficacy of integrated cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial. BMC psychiatry. 2013;13(1):132. 132. doi: https://doi.org/10.1186/1471-244X-13-132