TY - JOUR
T1 - Investigation of lattice infill parameters for additively manufactured bone fracture plates to reduce stress shielding
AU - Subasi, Omer
AU - Karaismailoglu, Bedri
AU - Ashkani-Esfahani, Soheil
AU - Lazoglu, Ismail
N1 - Funding Information: The chosen factor ranges mainly depend on manufacturing considerations. If t is chosen to be below 0.5 mm, there is an increased chance of warping and loss of cell wall rigidity due to the inherent limitations of the manufacturing process. The minimum value of d is chosen to be larger than the maximum value of t since in cases where t ≥ d, the infill will be 100% without a lattice. The value of α is chosen to be between 0° and 45°, as this range contains the only possible unique lattice orientations. Further angulation of the lattice about the z-axis only produces equivalent orientations included in this range. Using the designated values in combination, 27 different lattice infill plates are created for in silico testing. Two additional plates, the first being the benchmark plate with 100% infill, and the hollow plate, with 0% infill, are created as yardsticks for comparison. The plate wall thickness, the plate floor thickness, and the screw hole wall thickness have been set to 1 mm across all plate designs. Several modeled designs are displayed in Fig. 2c. The goal of the DOE is to identify the infill parameters that can produce a plate that minimizes K to best match the native bone tissue while not compromising on M for structural support. Publisher Copyright: © 2023 Elsevier Ltd
PY - 2023/7/1
Y1 - 2023/7/1
N2 - Background: Stress shielding is a detrimental phenomenon caused by the stiffness mismatch between metallic bone plates and bone tissue, which can hamper fracture healing. Additively manufactured plates can decrease plate stiffness and alleviate the stress shielding effect. Methods: Rectilinear lattice plates with varying cell sizes, wall thicknesses, and orientations are computationally generated. Finite element analysis is used to calculate the four-point bending stiffness and strength of the plates. The mechanical behaviors of three different lattice plates are also simulated under a simple diaphyseal fracture fixation scenario. Results: The study shows that with different combinations of lattice infill parameters, plates with up to 68% decrease in stiffness compared to the 100% infill plate can be created. Moreover, in the fixation simulations, the least stiff lattice plate displays 53% more average stress distribution at the healing callus region compared to the 100% infill plate. Conclusions: Using computational techniques, it has been demonstrated that additively manufactured stiffness-reduced bone plates can successfully address stress shielding with the strategic modulation of lattice infill parameters. Lattice plates with design versatility have the potential for use in various fracture fixation scenarios.
AB - Background: Stress shielding is a detrimental phenomenon caused by the stiffness mismatch between metallic bone plates and bone tissue, which can hamper fracture healing. Additively manufactured plates can decrease plate stiffness and alleviate the stress shielding effect. Methods: Rectilinear lattice plates with varying cell sizes, wall thicknesses, and orientations are computationally generated. Finite element analysis is used to calculate the four-point bending stiffness and strength of the plates. The mechanical behaviors of three different lattice plates are also simulated under a simple diaphyseal fracture fixation scenario. Results: The study shows that with different combinations of lattice infill parameters, plates with up to 68% decrease in stiffness compared to the 100% infill plate can be created. Moreover, in the fixation simulations, the least stiff lattice plate displays 53% more average stress distribution at the healing callus region compared to the 100% infill plate. Conclusions: Using computational techniques, it has been demonstrated that additively manufactured stiffness-reduced bone plates can successfully address stress shielding with the strategic modulation of lattice infill parameters. Lattice plates with design versatility have the potential for use in various fracture fixation scenarios.
KW - Additive manufacturing
KW - Bone plate
KW - Finite element analysis
KW - Lattice infill
KW - Stress shielding
UR - http://www.scopus.com/inward/record.url?scp=85160004308&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.compbiomed.2023.107062
DO - https://doi.org/10.1016/j.compbiomed.2023.107062
M3 - Article
C2 - 37235944
SN - 0010-4825
VL - 161
JO - Computers in Biology and Medicine
JF - Computers in Biology and Medicine
M1 - 107062
ER -