Investigation of serum response to PMP22, connexin 32 and P(0) in inflammatory neuropathies

M. S. Kwa; I. N. van Schaik; A. Brand; F. Baas; M. Vermeulen

doi:https://doi.org/10.1016/S0165-5728(01)00307-1

Investigation of serum response to PMP22, connexin 32 and P(0) in inflammatory neuropathies

M. S. Kwa, I. N. van Schaik, A. Brand, F. Baas, M. Vermeulen

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Abstract

We investigated serological immune responses against three major peripheral nerve myelin constituents in patients with immune-mediated neuropathies. Connexin 32 (Cx32), myelin protein zero (MPZ, P(0)) and peripheral myelin protein 22 (PMP22) were produced in Chinese hamster ovary (CHO)-K1 cells. From a panel of 25 Guillain-Barré syndrome (GBS) and 24 chronic inflammatory demyelinating polyneuropathy (CIDP) patients, only two patients showed reactivity towards Cx32 and P(0)

Original language	English
Pages (from-to)	220-225
Journal	Journal of Neuroimmunology
Volume	116
Issue number	2
DOIs	https://doi.org/10.1016/S0165-5728(01)00307-1
Publication status	Published - 2001

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https://doi.org/10.1016/S0165-5728(01)00307-1

Cite this

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title = "Investigation of serum response to PMP22, connexin 32 and P(0) in inflammatory neuropathies",

abstract = "We investigated serological immune responses against three major peripheral nerve myelin constituents in patients with immune-mediated neuropathies. Connexin 32 (Cx32), myelin protein zero (MPZ, P(0)) and peripheral myelin protein 22 (PMP22) were produced in Chinese hamster ovary (CHO)-K1 cells. From a panel of 25 Guillain-Barr{\'e} syndrome (GBS) and 24 chronic inflammatory demyelinating polyneuropathy (CIDP) patients, only two patients showed reactivity towards Cx32 and P(0)",

author = "Kwa, {M. S.} and {van Schaik}, {I. N.} and A. Brand and F. Baas and M. Vermeulen",

year = "2001",

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language = "English",

volume = "116",

pages = "220--225",

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issn = "0165-5728",

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TY - JOUR

T1 - Investigation of serum response to PMP22, connexin 32 and P(0) in inflammatory neuropathies

AU - Kwa, M. S.

AU - van Schaik, I. N.

AU - Brand, A.

AU - Baas, F.

AU - Vermeulen, M.

PY - 2001

Y1 - 2001

N2 - We investigated serological immune responses against three major peripheral nerve myelin constituents in patients with immune-mediated neuropathies. Connexin 32 (Cx32), myelin protein zero (MPZ, P(0)) and peripheral myelin protein 22 (PMP22) were produced in Chinese hamster ovary (CHO)-K1 cells. From a panel of 25 Guillain-Barré syndrome (GBS) and 24 chronic inflammatory demyelinating polyneuropathy (CIDP) patients, only two patients showed reactivity towards Cx32 and P(0)

AB - We investigated serological immune responses against three major peripheral nerve myelin constituents in patients with immune-mediated neuropathies. Connexin 32 (Cx32), myelin protein zero (MPZ, P(0)) and peripheral myelin protein 22 (PMP22) were produced in Chinese hamster ovary (CHO)-K1 cells. From a panel of 25 Guillain-Barré syndrome (GBS) and 24 chronic inflammatory demyelinating polyneuropathy (CIDP) patients, only two patients showed reactivity towards Cx32 and P(0)

U2 - https://doi.org/10.1016/S0165-5728(01)00307-1

DO - https://doi.org/10.1016/S0165-5728(01)00307-1

M3 - Article

C2 - 11438177

SN - 0165-5728

VL - 116

SP - 220

EP - 225

JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

IS - 2

ER -