Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells.

JF Arrighi; M Pion; M Wiznerowicz; T.B.H. Geijtenbeek; E Garcia; S. Abraham; F Leuba; V Dutoit; O Ducrey-Rundquist; Y. van Kooijk; D Trono; V Piguet; M Wiznerowics; V Piquet; Jean-François Arrighi; Yvette van Kooyk

doi:https://doi.org/10.1128/JVI.78.20.10848-10855.2004

Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells.

JF Arrighi, M Pion, M Wiznerowicz, T.B.H. Geijtenbeek, E Garcia, S. Abraham, F Leuba, V Dutoit, O Ducrey-Rundquist, Y. van Kooijk, D Trono, V Piguet, M Wiznerowics, V Piquet, Jean-François Arrighi, Yvette van Kooyk

Research output: Contribution to journal › Article › Academic › peer-review

110 Citations (Scopus)

Abstract

In the early events of human immunodeficiency virus type 1 (HIV-1) infection, immature dendritic cells (DCs) expressing the DC-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) receptor capture small amounts of HIV-1 on mucosal surfaces and spread viral infection to CD4

Original language	English
Pages (from-to)	10848-55
Number of pages	8
Journal	Journal of Virology
Volume	78
Issue number	20
Early online date	1 Oct 2004
DOIs	https://doi.org/10.1128/JVI.78.20.10848-10855.2004
Publication status	Published - Oct 2004

Keywords

Amino Acid Sequence
Animals
Cell Adhesion Molecules/chemistry
Cell Line
Dendritic Cells/metabolism
Gene Silencing
HIV Envelope Protein gp120/metabolism
HIV Infections/transmission
HIV-1/pathogenicity
HeLa Cells
Humans
Lectins, C-Type/chemistry
Lentivirus/genetics
Macaca mulatta
Molecular Sequence Data
Pan troglodytes
RNA Interference
RNA, Messenger/genetics
RNA, Small Interfering/genetics
Receptors, Cell Surface/chemistry
T-Lymphocytes/virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

https://doi.org/10.1128/JVI.78.20.10848-10855.2004

https://research.vu.nl/ws/files/1996955/170239.pdf

Cite this

Arrighi, JF., Pion, M., Wiznerowicz, M., Geijtenbeek, T. B. H., Garcia, E., Abraham, S., Leuba, F., Dutoit, V., Ducrey-Rundquist, O., van Kooijk, Y., Trono, D., Piguet, V., Wiznerowics, M., Piquet, V., Arrighi, J.-F., & van Kooyk, Y. (2004). Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells. Journal of Virology, 78(20), 10848-55. https://doi.org/10.1128/JVI.78.20.10848-10855.2004

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title = "Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells.",

abstract = "In the early events of human immunodeficiency virus type 1 (HIV-1) infection, immature dendritic cells (DCs) expressing the DC-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) receptor capture small amounts of HIV-1 on mucosal surfaces and spread viral infection to CD4",

keywords = "Amino Acid Sequence, Animals, Cell Adhesion Molecules/chemistry, Cell Line, Dendritic Cells/metabolism, Gene Silencing, HIV Envelope Protein gp120/metabolism, HIV Infections/transmission, HIV-1/pathogenicity, HeLa Cells, Humans, Lectins, C-Type/chemistry, Lentivirus/genetics, Macaca mulatta, Molecular Sequence Data, Pan troglodytes, RNA Interference, RNA, Messenger/genetics, RNA, Small Interfering/genetics, Receptors, Cell Surface/chemistry, T-Lymphocytes/virology",

author = "JF Arrighi and M Pion and M Wiznerowicz and T.B.H. Geijtenbeek and E Garcia and S. Abraham and F Leuba and V Dutoit and O Ducrey-Rundquist and {van Kooijk}, Y. and D Trono and V Piguet and M Wiznerowics and V Piquet and Jean-Fran{\c c}ois Arrighi and {van Kooyk}, Yvette",

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Arrighi, JF, Pion, M, Wiznerowicz, M, Geijtenbeek, TBH, Garcia, E, Abraham, S, Leuba, F, Dutoit, V, Ducrey-Rundquist, O, van Kooijk, Y, Trono, D, Piguet, V, Wiznerowics, M, Piquet, V, Arrighi, J-F & van Kooyk, Y 2004, 'Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells.', Journal of Virology, vol. 78, no. 20, pp. 10848-55. https://doi.org/10.1128/JVI.78.20.10848-10855.2004

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T1 - Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells.

AU - Arrighi, JF

AU - Pion, M

AU - Wiznerowicz, M

AU - Geijtenbeek, T.B.H.

AU - Garcia, E

AU - Abraham, S.

AU - Leuba, F

AU - Dutoit, V

AU - Ducrey-Rundquist, O

AU - van Kooijk, Y.

AU - Trono, D

AU - Piguet, V

AU - Wiznerowics, M

AU - Piquet, V

AU - Arrighi, Jean-François

AU - van Kooyk, Yvette

PY - 2004/10

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AB - In the early events of human immunodeficiency virus type 1 (HIV-1) infection, immature dendritic cells (DCs) expressing the DC-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) receptor capture small amounts of HIV-1 on mucosal surfaces and spread viral infection to CD4

KW - Amino Acid Sequence

KW - Animals

KW - Cell Adhesion Molecules/chemistry

KW - Cell Line

KW - Dendritic Cells/metabolism

KW - Gene Silencing

KW - HIV Envelope Protein gp120/metabolism

KW - HIV Infections/transmission

KW - HIV-1/pathogenicity

KW - HeLa Cells

KW - Humans

KW - Lectins, C-Type/chemistry

KW - Lentivirus/genetics

KW - Macaca mulatta

KW - Molecular Sequence Data

KW - Pan troglodytes

KW - RNA Interference

KW - RNA, Messenger/genetics

KW - RNA, Small Interfering/genetics

KW - Receptors, Cell Surface/chemistry

KW - T-Lymphocytes/virology

U2 - https://doi.org/10.1128/JVI.78.20.10848-10855.2004

DO - https://doi.org/10.1128/JVI.78.20.10848-10855.2004

M3 - Article

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