Malignant Hyperthermia During Cardiac Surgery Successfully Treated by Deep Hypothermia Using Cardiopulmonary Bypass: A Case Report

Luuk R. van den Bersselaar; Markus W. Hollmann; Jeanette M. M. H. van den Goor; Jacobus A. Winkelman; Marc M. J. Snoeck; Oskar T. Corsmit

doi:https://doi.org/10.1213/XAA.0000000000001546

Malignant Hyperthermia During Cardiac Surgery Successfully Treated by Deep Hypothermia Using Cardiopulmonary Bypass: A Case Report

Luuk R. van den Bersselaar, Markus W. Hollmann, Jeanette M. M. H. van den Goor, Jacobus A. Winkelman, Marc M. J. Snoeck, Oskar T. Corsmit

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1 Citation (Scopus)

Abstract

Malignant hyperthermia (MH) is a life-threatening hypermetabolic disorder triggered by volatile anesthetics and/or succinylcholine. We report a case of a 58-year-old patient with a type-A aortic dissection. After induction of general anesthesia, a hypermetabolic reaction was successfully treated by deep hypothermia using cardiopulmonary bypass. Dantrolene became available in theater after the hypermetabolism was already treated successfully by hypothermia. Because of a low suspicion of MH, dantrolene was not administered when it became available. The patient fully recovered, and MH susceptibility was confirmed. Cardiopulmonary bypass should be considered to treat MH in case dantrolene and conservative therapy are unavailable or insufficient.

Original language	English
Pages (from-to)	e01546
Journal	A&A practice
Volume	15
Issue number	11
DOIs	https://doi.org/10.1213/XAA.0000000000001546
Publication status	Published - 17 Nov 2021

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title = "Malignant Hyperthermia During Cardiac Surgery Successfully Treated by Deep Hypothermia Using Cardiopulmonary Bypass: A Case Report",

abstract = "Malignant hyperthermia (MH) is a life-threatening hypermetabolic disorder triggered by volatile anesthetics and/or succinylcholine. We report a case of a 58-year-old patient with a type-A aortic dissection. After induction of general anesthesia, a hypermetabolic reaction was successfully treated by deep hypothermia using cardiopulmonary bypass. Dantrolene became available in theater after the hypermetabolism was already treated successfully by hypothermia. Because of a low suspicion of MH, dantrolene was not administered when it became available. The patient fully recovered, and MH susceptibility was confirmed. Cardiopulmonary bypass should be considered to treat MH in case dantrolene and conservative therapy are unavailable or insufficient.",

author = "{van den Bersselaar}, {Luuk R.} and Hollmann, {Markus W.} and {van den Goor}, {Jeanette M. M. H.} and Winkelman, {Jacobus A.} and Snoeck, {Marc M. J.} and Corsmit, {Oskar T.}",

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AU - van den Goor, Jeanette M. M. H.

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AU - Snoeck, Marc M. J.

AU - Corsmit, Oskar T.

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AB - Malignant hyperthermia (MH) is a life-threatening hypermetabolic disorder triggered by volatile anesthetics and/or succinylcholine. We report a case of a 58-year-old patient with a type-A aortic dissection. After induction of general anesthesia, a hypermetabolic reaction was successfully treated by deep hypothermia using cardiopulmonary bypass. Dantrolene became available in theater after the hypermetabolism was already treated successfully by hypothermia. Because of a low suspicion of MH, dantrolene was not administered when it became available. The patient fully recovered, and MH susceptibility was confirmed. Cardiopulmonary bypass should be considered to treat MH in case dantrolene and conservative therapy are unavailable or insufficient.

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Malignant Hyperthermia During Cardiac Surgery Successfully Treated by Deep Hypothermia Using Cardiopulmonary Bypass: A Case Report

Abstract

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