Mechanisms of anesthesia-induced depression of myocardial function

S. de Hert, H. Adriaensen

Research output: Contribution to journalArticle*Academicpeer-review


Anesthetics may depress myocardial function. Part of this action is due to a direct negative inotropic effect of these agents. With the increasing knowledge on the cardiac excitation-contraction process, the understanding of the different possible mechanisms, underlying the anesthetic-induced myocardial depression also increases. The present state of knowledge on these possible mechanisms is reviewed and they are discussed as to their relative importance and their clinical relevance
Original languageEnglish
Pages (from-to)207-218
JournalActa Anaesthesiologica Belgica
Issue number3
Publication statusPublished - 1989

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