Methimazole-induced agranulocytosis preceded by transient granulocytopenia. A case report

N. H. Schut, W. M. Wiersinga, M. H. van Oers

Research output: Contribution to JournalComment / Letter to the editorAcademic

3 Citations (Scopus)


A 36-year-old patient, euthyroid under methimazole treatment, was admitted because of an active Graves' ophthalmopathy and found to have a transient granulocytopenia. Forty-five days after this episode she developed classical agranulocytosis because of which the methimazole was stopped. The agranulocytosis occurred more than 20 months after the initiation of antithyroid drug therapy. Other causes for the initial phase of granulocytopenia were not found
Original languageEnglish
Pages (from-to)71-73
JournalNetherlands journal of medicine
Issue number1-2
Publication statusPublished - 1993

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