Method for conditioning stem cells.

Antoni Bayes Genis; Aida Llucia Valldeperas; Carolina Soler Botija; Ramon Bragos Bardia; Francesc Xavier. Rosell Ferrer

Method for conditioning stem cells.

Antoni Bayes Genis (Inventor), Aida Llucia Valldeperas (Inventor), Carolina Soler Botija (Inventor), Ramon Bragos Bardia (Inventor), Francesc Xavier. Rosell Ferrer (Inventor)

Research output: Patent › Academic

Abstract

There is provided a method of stimulating an isolated stem cell comprising two stimulation steps: (a) cell mech. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more mech. pulses having a stretching value comprised from 5% to 15%, and a duration of time comprised from 300 to 700 ms, at a frequency comprised from 0.5 to 1.5 Hz; and (b) cell elec. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more elec. pulses having a potential value comprised from 0mv/cm to 1000mv/cm, and a duration of time comprised from 1 to 3 ms, at a frequency comprised from 0.5 to 1.5 Hz. There is also provided the cell obtainable by the method, further products comprising the cell such as solns. and scaffolds, and its uses in tissue engineering and regenerative therapy. [on SciFinder(R)]

Original language	English
Patent number	WO2017125159A1
Publication status	Published - 2017

Keywords

conditioning stem cell

Access to Document

http://www.mendeley.com/research/method-conditioning-stem-cells

Cite this

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title = "Method for conditioning stem cells.",

abstract = "There is provided a method of stimulating an isolated stem cell comprising two stimulation steps: (a) cell mech. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more mech. pulses having a stretching value comprised from 5% to 15%, and a duration of time comprised from 300 to 700 ms, at a frequency comprised from 0.5 to 1.5 Hz; and (b) cell elec. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more elec. pulses having a potential value comprised from 0mv/cm to 1000mv/cm, and a duration of time comprised from 1 to 3 ms, at a frequency comprised from 0.5 to 1.5 Hz. There is also provided the cell obtainable by the method, further products comprising the cell such as solns. and scaffolds, and its uses in tissue engineering and regenerative therapy. [on SciFinder(R)]",

keywords = "conditioning stem cell",

author = "{Bayes Genis}, Antoni and {Llucia Valldeperas}, Aida and {Soler Botija}, Carolina and {Bragos Bardia}, Ramon and {Rosell Ferrer}, {Francesc Xavier.}",

year = "2017",

language = "English",

publisher = "Universitat Politecnica de Catalunya, Spain; Fundacio Institut d'Investigacio en Ciencies de la Salut Germans Trias I Pujol .",

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TY - PAT

T1 - Method for conditioning stem cells.

AU - Bayes Genis, Antoni

AU - Llucia Valldeperas, Aida

AU - Soler Botija, Carolina

AU - Bragos Bardia, Ramon

AU - Rosell Ferrer, Francesc Xavier.

PY - 2017

Y1 - 2017

N2 - There is provided a method of stimulating an isolated stem cell comprising two stimulation steps: (a) cell mech. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more mech. pulses having a stretching value comprised from 5% to 15%, and a duration of time comprised from 300 to 700 ms, at a frequency comprised from 0.5 to 1.5 Hz; and (b) cell elec. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more elec. pulses having a potential value comprised from 0mv/cm to 1000mv/cm, and a duration of time comprised from 1 to 3 ms, at a frequency comprised from 0.5 to 1.5 Hz. There is also provided the cell obtainable by the method, further products comprising the cell such as solns. and scaffolds, and its uses in tissue engineering and regenerative therapy. [on SciFinder(R)]

AB - There is provided a method of stimulating an isolated stem cell comprising two stimulation steps: (a) cell mech. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more mech. pulses having a stretching value comprised from 5% to 15%, and a duration of time comprised from 300 to 700 ms, at a frequency comprised from 0.5 to 1.5 Hz; and (b) cell elec. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more elec. pulses having a potential value comprised from 0mv/cm to 1000mv/cm, and a duration of time comprised from 1 to 3 ms, at a frequency comprised from 0.5 to 1.5 Hz. There is also provided the cell obtainable by the method, further products comprising the cell such as solns. and scaffolds, and its uses in tissue engineering and regenerative therapy. [on SciFinder(R)]

KW - conditioning stem cell

M3 - Patent

M1 - WO2017125159A1

PB - Universitat Politecnica de Catalunya, Spain; Fundacio Institut d'Investigacio en Ciencies de la Salut Germans Trias I Pujol .

ER -