Microwave irradiation and cross-linking of collagen

C. E. Visser; A. B. Voute; J. Oosting; M. E. Boon; L. P. Kok

doi:https://doi.org/10.1016/0142-9612(92)90092-3

Microwave irradiation and cross-linking of collagen

C. E. Visser, A. B. Voute, J. Oosting, M. E. Boon, L. P. Kok

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Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

In a multifactorial experiment, dermal sheep collagen was treated in diluted glutaraldehyde solutions, 70% ethyl alcohol, Cialit 1:5000, and distilled water for 1, 3 and 5 min, respectively, in combination with microwave irradiation at different temperature settings. The shrinkage temperature indicating the degree of cross-linking achieved was then determined. Treatment in 0.65% glutaraldehyde with microwave irradiation setting for 60 degrees C resulted in the maximum shrinkage temperature within 1 min, whilst at the lower setting of 50 degrees C, the maximum shrinkage temperature for both glutaraldehyde solutions is only reached after 5 min. Neither microwave irradiation by itself, Cialit or ethyl alcohol induce cross-linking of collagen fibres. These findings are relevant for implant studies

Original language	English
Pages (from-to)	34-37
Journal	Biomaterials
Volume	13
Issue number	1
DOIs	https://doi.org/10.1016/0142-9612(92)90092-3
Publication status	Published - 1992

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https://doi.org/10.1016/0142-9612(92)90092-3

Cite this

@article{bc2331c113e24a609546660479dd6775,

title = "Microwave irradiation and cross-linking of collagen",

abstract = "In a multifactorial experiment, dermal sheep collagen was treated in diluted glutaraldehyde solutions, 70% ethyl alcohol, Cialit 1:5000, and distilled water for 1, 3 and 5 min, respectively, in combination with microwave irradiation at different temperature settings. The shrinkage temperature indicating the degree of cross-linking achieved was then determined. Treatment in 0.65% glutaraldehyde with microwave irradiation setting for 60 degrees C resulted in the maximum shrinkage temperature within 1 min, whilst at the lower setting of 50 degrees C, the maximum shrinkage temperature for both glutaraldehyde solutions is only reached after 5 min. Neither microwave irradiation by itself, Cialit or ethyl alcohol induce cross-linking of collagen fibres. These findings are relevant for implant studies",

author = "Visser, {C. E.} and Voute, {A. B.} and J. Oosting and Boon, {M. E.} and Kok, {L. P.}",

year = "1992",

doi = "https://doi.org/10.1016/0142-9612(92)90092-3",

language = "English",

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journal = "Biomaterials",

issn = "0142-9612",

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TY - JOUR

T1 - Microwave irradiation and cross-linking of collagen

AU - Visser, C. E.

AU - Voute, A. B.

AU - Oosting, J.

AU - Boon, M. E.

AU - Kok, L. P.

PY - 1992

Y1 - 1992

N2 - In a multifactorial experiment, dermal sheep collagen was treated in diluted glutaraldehyde solutions, 70% ethyl alcohol, Cialit 1:5000, and distilled water for 1, 3 and 5 min, respectively, in combination with microwave irradiation at different temperature settings. The shrinkage temperature indicating the degree of cross-linking achieved was then determined. Treatment in 0.65% glutaraldehyde with microwave irradiation setting for 60 degrees C resulted in the maximum shrinkage temperature within 1 min, whilst at the lower setting of 50 degrees C, the maximum shrinkage temperature for both glutaraldehyde solutions is only reached after 5 min. Neither microwave irradiation by itself, Cialit or ethyl alcohol induce cross-linking of collagen fibres. These findings are relevant for implant studies

AB - In a multifactorial experiment, dermal sheep collagen was treated in diluted glutaraldehyde solutions, 70% ethyl alcohol, Cialit 1:5000, and distilled water for 1, 3 and 5 min, respectively, in combination with microwave irradiation at different temperature settings. The shrinkage temperature indicating the degree of cross-linking achieved was then determined. Treatment in 0.65% glutaraldehyde with microwave irradiation setting for 60 degrees C resulted in the maximum shrinkage temperature within 1 min, whilst at the lower setting of 50 degrees C, the maximum shrinkage temperature for both glutaraldehyde solutions is only reached after 5 min. Neither microwave irradiation by itself, Cialit or ethyl alcohol induce cross-linking of collagen fibres. These findings are relevant for implant studies

U2 - https://doi.org/10.1016/0142-9612(92)90092-3

DO - https://doi.org/10.1016/0142-9612(92)90092-3

M3 - Article

C2 - 1543806

SN - 0142-9612

VL - 13

SP - 34

EP - 37

JO - Biomaterials

JF - Biomaterials

IS - 1

ER -