Model of coronary hemodynamics during radiographic contrast injection

Maria Siebes, Jan J. Piek, Jos A.E. Spaan

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Serial quantitative angiographic studies are frequently employed to assess the effect of dietary or mechanical interventions on the severity of coronary artery stenosis and angiographic conditions that may alter coronary diameter via changes in pressure need to be avoided. The purpose of this study was to investigate the extent of hemodynamic changes introduced during the injection of radiographic contrast into the coronary ostium. A linear resistance model was developed to simulate this event for different rates of injection (2-6 ml/sec) and resistance ratios (Rcor/Rcath= 40 and 80). The results show an increase in coronary pressure between 7 and 44 mmHg at the time of injection, which depends primarily on the injection rate and the resistance posed by the guiding catheter in the coronary ostium. These data are consistent with earlier experimental results and point to the importance of standardizing contrast injections for QCA studies.

Original languageEnglish
Title of host publicationProceedings 18th International Conference of the IEEE Engineering in Medicine and Biology Society
Pages1754-1755
Number of pages2
Volume4
Publication statusPublished - 1996
EventProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 4 (of 5) - Amsterdam, Neth
Duration: 31 Oct 19963 Nov 1996

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Conference

ConferenceProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 4 (of 5)
CityAmsterdam, Neth
Period31/10/963/11/96

Cite this