TY - JOUR
T1 - Network meta-analyses in reproductive medicine: challenges and opportunities
AU - Wang, Rui
AU - Seidler, Anna Lene
AU - Askie, Lisa
AU - Norman, Robert J.
AU - Bhattacharya, Siladitya
AU - van Wely, Madelon
AU - Mol, Ben Willem
N1 - Funding Information: R.W. was supported by an Australian Government Research Training Program (RTP) Scholarship. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Publisher Copyright: © The Author(s) 2020. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please email: [email protected] Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Network meta-analysis allows researchers to synthesise both direct and indirect evidence, thus enabling simultaneous comparisons of multiple treatments. A relatively recent addition to evidence synthesis in reproductive medicine, this approach has become increasingly popular. Yet, the underlying assumptions of network meta-analyses, which drive the validity of their findings, have been frequently ignored. In this article, we discuss the strengths and limitations of network meta-analyses. In addition, we present an overview of published network meta-analyses in reproductive medicine, summarize their challenges and provide insights into future research opportunities.
AB - Network meta-analysis allows researchers to synthesise both direct and indirect evidence, thus enabling simultaneous comparisons of multiple treatments. A relatively recent addition to evidence synthesis in reproductive medicine, this approach has become increasingly popular. Yet, the underlying assumptions of network meta-analyses, which drive the validity of their findings, have been frequently ignored. In this article, we discuss the strengths and limitations of network meta-analyses. In addition, we present an overview of published network meta-analyses in reproductive medicine, summarize their challenges and provide insights into future research opportunities.
KW - Certainty of evidence
KW - Evidence synthesis
KW - Infertility
KW - Meta-analysis
KW - Network meta-analysis
KW - Reporting
KW - Reproductive medicine
KW - Systematic review
KW - Transitivity
UR - http://www.scopus.com/inward/record.url?scp=85089127909&partnerID=8YFLogxK
U2 - https://doi.org/10.1093/humrep/deaa126
DO - https://doi.org/10.1093/humrep/deaa126
M3 - Review article
C2 - 32662508
SN - 0268-1161
VL - 35
SP - 1723
EP - 1731
JO - Human reproduction (Oxford, England)
JF - Human reproduction (Oxford, England)
IS - 8
ER -