Neuroanatomy of Obsessive Compulsive and Related Disorders

David Mataix-Cols, Odile A. Van Den Heuvel

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

5 Citations (Scopus)


Obsessive-compulsive disorder (OCD) shares features and often co-occurs with other anxiety disorders, as well as with other psychiatric conditions classified elsewhere in the Diagnostic and Statistical Manual (DSM-IV), the socalled "OCD spectrum disorders." Neurobiologically, it is unclear how all these disorders relate to one another. The picture is further complicated by the clinical heterogeneity of OCD. This chapter will review the literature on the common and distinct neural correlates of OCD vis-à-vis other anxiety and "OCD spectrum" disorders. Furthermore, the question of whether partially distinct neural systems subserve the different symptom dimensions of OCD will be examined. Particular attention will be paid to hoarding, which is emerging as a distinct entity from OCD. Finally, new insights from cognitive and affective neuroscience will be reviewed before concluding with a summary and recommendations for future research.

Original languageEnglish
Title of host publicationThe Oxford Handbook of Obsessive Compulsive and Spectrum Disorders
PublisherOxford University Press
ISBN (Electronic)9780199940561
ISBN (Print)9780195376210
Publication statusPublished - 18 Sept 2012


  • Anxiety disorders
  • Body dysmorphic disorder
  • Brain
  • Hoarding
  • Neuroanatomy
  • Neuroimaging
  • OCD
  • Symptom dimensions
  • Tourette's syndrome
  • Trichotillomania

Cite this