TY - JOUR
T1 - Neuromodulation in obsessive-compulsive disorder
AU - Bais, Melisse
AU - Figee, Martijn
AU - Denys, Damiaan
PY - 2014
Y1 - 2014
N2 - Neuromodulation techniques in obsessive-compulsive disorder (OCD) involve electroconvulsive therapy (ECT), transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS), and deep brain stimulation (DBS). This article reviews the available literature on the efficacy and applicability of these techniques in OCD. ECT is used for the treatment of comorbid depression or psychosis. One case report on tDCS showed no effects in OCD. Low-frequency TMS provides significant but mostly transient improvement of obsessive-compulsive symptoms. DBS shows a response rate of 60% in open and sham-controlled studies. In OCD, it can be concluded that DBS, although more invasive, is the most efficacious technique
AB - Neuromodulation techniques in obsessive-compulsive disorder (OCD) involve electroconvulsive therapy (ECT), transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS), and deep brain stimulation (DBS). This article reviews the available literature on the efficacy and applicability of these techniques in OCD. ECT is used for the treatment of comorbid depression or psychosis. One case report on tDCS showed no effects in OCD. Low-frequency TMS provides significant but mostly transient improvement of obsessive-compulsive symptoms. DBS shows a response rate of 60% in open and sham-controlled studies. In OCD, it can be concluded that DBS, although more invasive, is the most efficacious technique
U2 - https://doi.org/10.1016/j.psc.2014.06.003
DO - https://doi.org/10.1016/j.psc.2014.06.003
M3 - Article
C2 - 25150569
SN - 1056-4993
VL - 37
SP - 393
EP - 413
JO - Child and Adolescent Psychiatric Clinics of North America
JF - Child and Adolescent Psychiatric Clinics of North America
IS - 3
ER -