TY - JOUR
T1 - Normal cognitive performance in patients with chronic alcoholism in contrast to patients with Korsakoff's syndrome
AU - Krabbendam, Lydia
AU - Visser, Pieter Jelle
AU - Derix, Mayke M.A.
AU - Verhey, Frans
AU - Hofman, Paul
AU - Verhoeven, Willem
AU - Tuinier, Siegfried
AU - Jolles, Jelle
PY - 2000/1/1
Y1 - 2000/1/1
N2 - This study investigated which cognitive deficits are associated with chronic alcoholism. Neuropsychological profiles and MRI brain structure volumes of 14 patients with Korsakoff's syndrome, 15 patients with chronic alcoholism, and 16 healthy control subjects were compared. The patients with alcoholism had a normal cognitive performance and normal brain structure volumes. The patients with Korsacoff's syndrome had performance deficits on tests of memory, visuoperceptual, and executive functions, as well as reduced brain structure volumes. The results suggest that the cognitive deficits cannot be ascribed to mere chronic consumption of alcohol. If cognitive deficits are present in patients with chronic alcoholism, this may point to an underlying brain disorder.
AB - This study investigated which cognitive deficits are associated with chronic alcoholism. Neuropsychological profiles and MRI brain structure volumes of 14 patients with Korsakoff's syndrome, 15 patients with chronic alcoholism, and 16 healthy control subjects were compared. The patients with alcoholism had a normal cognitive performance and normal brain structure volumes. The patients with Korsacoff's syndrome had performance deficits on tests of memory, visuoperceptual, and executive functions, as well as reduced brain structure volumes. The results suggest that the cognitive deficits cannot be ascribed to mere chronic consumption of alcohol. If cognitive deficits are present in patients with chronic alcoholism, this may point to an underlying brain disorder.
UR - http://www.scopus.com/inward/record.url?scp=0033967341&partnerID=8YFLogxK
U2 - https://doi.org/10.1176/jnp.12.1.44
DO - https://doi.org/10.1176/jnp.12.1.44
M3 - Article
C2 - 10678512
SN - 0895-0172
VL - 12
SP - 44
EP - 50
JO - Journal of neuropsychiatry and clinical neurosciences
JF - Journal of neuropsychiatry and clinical neurosciences
IS - 1
ER -