Novel approaches for the treatment of rheumatoid arthritis: lessons from the evaluation of synovial biomarkers in clinical trials

Daniëlle M. Gerlag, Paul P. Tak

Research output: Contribution to journalArticleAcademicpeer-review


The analysis of synovial biomarkers is increasingly used in the context of innovative trial design in rheumatoid arthritis (RA). This approach, which is generally well tolerated by patients, has been used to provide insight into the pathogenesis of RA and the mechanism of action of therapy, as well as for screening purposes during early drug development
Original languageEnglish
Pages (from-to)311-323
JournalBest practice & research. Clinical rheumatology
Issue number2
Publication statusPublished - 2008

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