Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells

Willem J. J. Falkenburg; Marit Jalink; Marie José Kersten; Jochem B. Buil; Karin van Dijk

doi:https://doi.org/10.1016/j.mmcr.2022.10.002

Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells

Willem J. J. Falkenburg, Marit Jalink, Marie José Kersten, Jochem B. Buil, Karin van Dijk

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Chimeric antigen receptor (CAR-) T cell therapy is a relatively new form of immunotherapy for hematological malignancies. Although patients are at increased risk of infection following CAR-T cell therapy, reports of fungal infections are scarce. We report a case of Scedosporium apiospermum infection causing bursitis of the elbow in a lymphoma patient after treatment with CAR-T cells. The fungal bursitis relapsed under posaconazole treatment, but was cured after surgical extirpation of the bursa.

Original language	English
Pages (from-to)	33-35
Number of pages	3
Journal	MEDICAL MYCOLOGY CASE REPORTS
Volume	38
DOIs	https://doi.org/10.1016/j.mmcr.2022.10.002
Publication status	Published - 1 Dec 2022

Keywords

Bursitis
CAR-T cell therapy
Posaconazole
Scedosporium apiospermum
Voriconazole

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https://doi.org/10.1016/j.mmcr.2022.10.002

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title = "Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells",

abstract = "Chimeric antigen receptor (CAR-) T cell therapy is a relatively new form of immunotherapy for hematological malignancies. Although patients are at increased risk of infection following CAR-T cell therapy, reports of fungal infections are scarce. We report a case of Scedosporium apiospermum infection causing bursitis of the elbow in a lymphoma patient after treatment with CAR-T cells. The fungal bursitis relapsed under posaconazole treatment, but was cured after surgical extirpation of the bursa.",

keywords = "Bursitis, CAR-T cell therapy, Posaconazole, Scedosporium apiospermum, Voriconazole",

author = "Falkenburg, {Willem J. J.} and Marit Jalink and Kersten, {Marie Jos{\'e}} and Buil, {Jochem B.} and {van Dijk}, Karin",

note = "Funding Information: We thank Dionne Hoogendoorn for the microscopy picture. Publisher Copyright: {\textcopyright} 2022 The Authors",

year = "2022",

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doi = "https://doi.org/10.1016/j.mmcr.2022.10.002",

language = "English",

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pages = "33--35",

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T1 - Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells

AU - Falkenburg, Willem J. J.

AU - Jalink, Marit

AU - Kersten, Marie José

AU - Buil, Jochem B.

AU - van Dijk, Karin

PY - 2022/12/1

Y1 - 2022/12/1

N2 - Chimeric antigen receptor (CAR-) T cell therapy is a relatively new form of immunotherapy for hematological malignancies. Although patients are at increased risk of infection following CAR-T cell therapy, reports of fungal infections are scarce. We report a case of Scedosporium apiospermum infection causing bursitis of the elbow in a lymphoma patient after treatment with CAR-T cells. The fungal bursitis relapsed under posaconazole treatment, but was cured after surgical extirpation of the bursa.

AB - Chimeric antigen receptor (CAR-) T cell therapy is a relatively new form of immunotherapy for hematological malignancies. Although patients are at increased risk of infection following CAR-T cell therapy, reports of fungal infections are scarce. We report a case of Scedosporium apiospermum infection causing bursitis of the elbow in a lymphoma patient after treatment with CAR-T cells. The fungal bursitis relapsed under posaconazole treatment, but was cured after surgical extirpation of the bursa.

KW - Bursitis

KW - CAR-T cell therapy

KW - Posaconazole

KW - Scedosporium apiospermum

KW - Voriconazole

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DO - https://doi.org/10.1016/j.mmcr.2022.10.002

M3 - Article

C2 - 36353268

SN - 2211-7539

VL - 38

SP - 33

EP - 35

JO - MEDICAL MYCOLOGY CASE REPORTS

JF - MEDICAL MYCOLOGY CASE REPORTS

ER -

Olecranon bursitis caused by Scedosporium apiospermum in a patient treated with CAR-T cells

Abstract

Keywords

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