TY - JOUR
T1 - One-year follow-up results of a randomized controlled clinical trial on internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years
AU - Spek, V.
AU - Cuijpers, P.
AU - Nyklicek, I.
AU - Smits, N
AU - Riper, H.
AU - Keyzer, J.
AU - Pop, V.
AU - Nyklíček, I.
PY - 2008/5
Y1 - 2008/5
N2 - Background. Internet-based cognitive behaviour therapy (CBT) is a promising new approach for the treatment of depressive symptoms. The current study had two aims: (1) to determine whether, after 1 year, an internet-based CBT intervention was more effective than a waiting-list control group; and (2) to determine whether the effect of the internet-based CBT differed from the group CBT intervention, 1 year after the start of treatment. Method. A total of 191 women and 110 men (mean age=55 years, s.d.=4.6) with subthreshold depression were randomized into internet-based treatment, group CBT (Lewinsohn's Coping with Depression Course), or a waiting-list control condition. The main outcome measure was treatment response after 1 year, defined as the difference in pretreatment and follow-up scores on the Beck Depression Inventory (BDI). Missing data were imputed using the multiple imputation procedure of data augmentation. Analyses were performed using multiple imputation inference. Results. In the waiting-list control group, we found a pretreatment to follow-up improvement effect size of 0.69, which was 0.62 in the group CBT condition and 1.22 with the internet-based treatment condition. Simple contrasts showed a significant difference between the waiting-list condition and internet-based treatment (p=0.03) and no difference between both treatment conditions (p=0.08). Conclusions. People aged over 50 years with subthreshold depression can still benefit from internet-based CBT 1 year after the start of treatment.
AB - Background. Internet-based cognitive behaviour therapy (CBT) is a promising new approach for the treatment of depressive symptoms. The current study had two aims: (1) to determine whether, after 1 year, an internet-based CBT intervention was more effective than a waiting-list control group; and (2) to determine whether the effect of the internet-based CBT differed from the group CBT intervention, 1 year after the start of treatment. Method. A total of 191 women and 110 men (mean age=55 years, s.d.=4.6) with subthreshold depression were randomized into internet-based treatment, group CBT (Lewinsohn's Coping with Depression Course), or a waiting-list control condition. The main outcome measure was treatment response after 1 year, defined as the difference in pretreatment and follow-up scores on the Beck Depression Inventory (BDI). Missing data were imputed using the multiple imputation procedure of data augmentation. Analyses were performed using multiple imputation inference. Results. In the waiting-list control group, we found a pretreatment to follow-up improvement effect size of 0.69, which was 0.62 in the group CBT condition and 1.22 with the internet-based treatment condition. Simple contrasts showed a significant difference between the waiting-list condition and internet-based treatment (p=0.03) and no difference between both treatment conditions (p=0.08). Conclusions. People aged over 50 years with subthreshold depression can still benefit from internet-based CBT 1 year after the start of treatment.
KW - Cognitive behaviour therapy
KW - Depression
KW - Internet
UR - http://www.scopus.com/inward/record.url?scp=41649117099&partnerID=8YFLogxK
U2 - https://doi.org/10.1017/S0033291707002590
DO - https://doi.org/10.1017/S0033291707002590
M3 - Article
C2 - 18205965
SN - 0033-2917
VL - 38
SP - 635
EP - 639
JO - Psychological Medicine
JF - Psychological Medicine
IS - 5
ER -